Identification of novel germline polymorphisms governing capecitabine sensitivity

Keyphrases

• Capecitabine 100%
• Germline Polymorphism 100%
• Single nucleotide Polymorphism 60%
• Meta-analysis 40%
• Reductase 30%
• SNP 20%
• Genome-wide Association Study 20%
• 5-fluorouracil (5-FU) 20%
• Methyltransferase 20%
• Antitumor Efficacy 20%
• Patient Selection 20%
• Genome-wide Significance 20%
• Germline 20%
• Related Compounds 10%
• Novel Genes 10%
• Human Cell Lines 10%
• Breast Cancer Treatment 10%
• World Population 10%
• Actin 10%
• Cancer Chemotherapy 10%
• Methionine 10%
• Chromatin 10%
• American Cancer Society 10%
• Asparagine 10%
• Biosynthesis Pathway 10%
• Adenylate Cyclase 10%
• Gastric Cancer 10%
• Colorectal Cancer Prevention 10%
• Intrapopulation 10%
• Folate Metabolism 10%
• SMARCAD1 10%
• Oral 5-fluorouracil 10%
• Folate Biosynthesis 10%
• Genomic Predictors 10%
• Matrix-based 10%
• 5-methyltetrahydrofolate-homocysteine Methyltransferase 10%
• Metabolic Pathways 10%
• Missense Variant 10%
• Ethnic Population 10%
• SWItch/sucrose Non-fermentable 10%
• 5-Fluorouracil Prodrugs 10%

Biochemistry, Genetics and Molecular Biology

• Germline 100%
• Germ Cell 100%
• Capecitabine 100%
• Single-Nucleotide Polymorphism 60%
• Reductase 30%
• Oxidoreductase 30%
• Fluorouracil 30%
• Single Nucleotide Polymorphism 20%
• Genome-Wide Association Study 20%
• Methyltransferase 20%
• Anabolism 10%
• Metabolic Pathway 10%
• Sucrose 10%
• Asparagine 10%
• Missense 10%
• Enzyme 10%
• Chromatin 10%
• Actin 10%
• Folic Acid 10%
• Adenylate Cyclase 10%
• Methionine Synthase 10%
• Genomics 10%
• Serine 10%
• Methionine 10%