Identification of bacteria in formalin-fixed, paraffin-embedded heart valve tissue via 16S rRNA gene nucleotide sequencing

Kavita Imrit, Michael Goldfischer, Jie Wang, Jaime Green, Jerome Levine, Joseph Lombardo, Tao Hong

Research output: Contribution to journalArticlepeer-review

34 Scopus citations

Abstract

We applied 16S rRNA gene sequencing to identify bacterial species present in formalin-fixed, paraffin-embedded heart valve tissue. In 40% (12/30) of the cases, we were able to identify the bacterium to the species-genus level. For more recent cases (≤4 years), the success rate was significantly improved, to 70% (P < 0.001).

Original languageEnglish (US)
Pages (from-to)2609-2611
Number of pages3
JournalJournal of clinical microbiology
Volume44
Issue number7
DOIs
StatePublished - Jul 2006

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