Identification of antigens for use in immunodiagnosis of Taenia saginata cysticercosis

E. I.P. Kamanga-Sollo; K. J. Lindqvist; A. J. Musoke

doi:10.1016/0034-5288(91)90100-3

Identification of antigens for use in immunodiagnosis of Taenia saginata cysticercosis

E. I.P. Kamanga-Sollo, K. J. Lindqvist, A. J. Musoke

Research output: Contribution to journal › Article › peer-review

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Abstract

Fifteen metacestode antigens from Taenia saginata were defined by Laurell crossed immunoelectrophoresis and investigated for their potential use in immunodiagnosis of bovine cysticercosis. Several antigens cross reacted with those of some common cattle parasites. Three of the antigens, designated as numbers 4, 8 and 11, were selected on the basis of their restricted cross reactions and were isolated by affinity chromatography. These antigens showed high sensitivity and specificity values in the enzyme-linked immunosorbent assay (Elisa) for serodiagnosis of bovine cysticercosis.

Original language	English (US)
Pages (from-to)	162-169
Number of pages	8
Journal	Research in veterinary science
Volume	50
Issue number	2
DOIs	https://doi.org/10.1016/0034-5288(91)90100-3
State	Published - Mar 1991
Externally published	Yes

Bibliographical note

Funding Information:
This work was supported by grants from the Norwegian Agency for International Development (NORAD) and in part by the McNamara fellowship programme. We would like to thank Dr V. M. Nantulya for his critical comments; Ms C. Nkonge for technical assistance and Ms Doris Churi for typing the manuscript.

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title = "Identification of antigens for use in immunodiagnosis of Taenia saginata cysticercosis",

abstract = "Fifteen metacestode antigens from Taenia saginata were defined by Laurell crossed immunoelectrophoresis and investigated for their potential use in immunodiagnosis of bovine cysticercosis. Several antigens cross reacted with those of some common cattle parasites. Three of the antigens, designated as numbers 4, 8 and 11, were selected on the basis of their restricted cross reactions and were isolated by affinity chromatography. These antigens showed high sensitivity and specificity values in the enzyme-linked immunosorbent assay (Elisa) for serodiagnosis of bovine cysticercosis.",

author = "Kamanga-Sollo, {E. I.P.} and Lindqvist, {K. J.} and Musoke, {A. J.}",

note = "Funding Information: This work was supported by grants from the Norwegian Agency for International Development (NORAD) and in part by the McNamara fellowship programme. We would like to thank Dr V. M. Nantulya for his critical comments; Ms C. Nkonge for technical assistance and Ms Doris Churi for typing the manuscript.",

year = "1991",

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doi = "10.1016/0034-5288(91)90100-3",

language = "English (US)",

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T1 - Identification of antigens for use in immunodiagnosis of Taenia saginata cysticercosis

AU - Kamanga-Sollo, E. I.P.

AU - Lindqvist, K. J.

AU - Musoke, A. J.

N1 - Funding Information: This work was supported by grants from the Norwegian Agency for International Development (NORAD) and in part by the McNamara fellowship programme. We would like to thank Dr V. M. Nantulya for his critical comments; Ms C. Nkonge for technical assistance and Ms Doris Churi for typing the manuscript.

PY - 1991/3

Y1 - 1991/3

N2 - Fifteen metacestode antigens from Taenia saginata were defined by Laurell crossed immunoelectrophoresis and investigated for their potential use in immunodiagnosis of bovine cysticercosis. Several antigens cross reacted with those of some common cattle parasites. Three of the antigens, designated as numbers 4, 8 and 11, were selected on the basis of their restricted cross reactions and were isolated by affinity chromatography. These antigens showed high sensitivity and specificity values in the enzyme-linked immunosorbent assay (Elisa) for serodiagnosis of bovine cysticercosis.

AB - Fifteen metacestode antigens from Taenia saginata were defined by Laurell crossed immunoelectrophoresis and investigated for their potential use in immunodiagnosis of bovine cysticercosis. Several antigens cross reacted with those of some common cattle parasites. Three of the antigens, designated as numbers 4, 8 and 11, were selected on the basis of their restricted cross reactions and were isolated by affinity chromatography. These antigens showed high sensitivity and specificity values in the enzyme-linked immunosorbent assay (Elisa) for serodiagnosis of bovine cysticercosis.

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Identification of antigens for use in immunodiagnosis of Taenia saginata cysticercosis

Abstract

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