Identification of antigens for use in immunodiagnosis of Taenia saginata cysticercosis

E. I.P. Kamanga-Sollo, K. J. Lindqvist, A. J. Musoke

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Abstract

Fifteen metacestode antigens from Taenia saginata were defined by Laurell crossed immunoelectrophoresis and investigated for their potential use in immunodiagnosis of bovine cysticercosis. Several antigens cross reacted with those of some common cattle parasites. Three of the antigens, designated as numbers 4, 8 and 11, were selected on the basis of their restricted cross reactions and were isolated by affinity chromatography. These antigens showed high sensitivity and specificity values in the enzyme-linked immunosorbent assay (Elisa) for serodiagnosis of bovine cysticercosis.

Original languageEnglish (US)
Pages (from-to)162-169
Number of pages8
JournalResearch in veterinary science
Volume50
Issue number2
DOIs
StatePublished - Mar 1991

Bibliographical note

Funding Information:
This work was supported by grants from the Norwegian Agency for International Development (NORAD) and in part by the McNamara fellowship programme. We would like to thank Dr V. M. Nantulya for his critical comments; Ms C. Nkonge for technical assistance and Ms Doris Churi for typing the manuscript.

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