Identification of a pegivirus (GB virus-like virus) that infects horses

Amit Kapoor; Peter Simmonds; John M. Cullen; Troels K.H. Scheel; Jan L. Medina; Federico Giannitti; Eiko Nishiuchi; Kenny V. Brock; Peter D. Burbelo; Charles M. Rice; W. Ian Lipkin

doi:10.1128/JVI.00324-13

Identification of a pegivirus (GB virus-like virus) that infects horses

Amit Kapoor, Peter Simmonds, John M. Cullen, Troels K.H. Scheel, Jan L. Medina, Federico Giannitti, Eiko Nishiuchi, Kenny V. Brock, Peter D. Burbelo, Charles M. Rice, W. Ian Lipkin

Research output: Contribution to journal › Article › peer-review

81 Scopus citations

Abstract

The recent identification of nonprimate hepaciviruses in dogs and then in horses prompted us to look for pegiviruses (GB viruslike viruses) in these species. Although none were detected in canines, we found widespread natural infection of horses by a novel pegivirus. Unique genomic features and phylogenetic analyses confirmed that the tentatively named equine pegivirus (EPgV) represents a novel species within the Pegivirus genus. We also determined that EPgV causes persistent viremia whereas its clinical significance is undetermined.

Original language	English (US)
Pages (from-to)	7185-7190
Number of pages	6
Journal	Journal of virology
Volume	87
Issue number	12
DOIs	https://doi.org/10.1128/JVI.00324-13
State	Published - Jun 2013
Externally published	Yes

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title = "Identification of a pegivirus (GB virus-like virus) that infects horses",

abstract = "The recent identification of nonprimate hepaciviruses in dogs and then in horses prompted us to look for pegiviruses (GB viruslike viruses) in these species. Although none were detected in canines, we found widespread natural infection of horses by a novel pegivirus. Unique genomic features and phylogenetic analyses confirmed that the tentatively named equine pegivirus (EPgV) represents a novel species within the Pegivirus genus. We also determined that EPgV causes persistent viremia whereas its clinical significance is undetermined.",

author = "Amit Kapoor and Peter Simmonds and Cullen, {John M.} and Scheel, {Troels K.H.} and Medina, {Jan L.} and Federico Giannitti and Eiko Nishiuchi and Brock, {Kenny V.} and Burbelo, {Peter D.} and Rice, {Charles M.} and Lipkin, {W. Ian}",

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language = "English (US)",

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AU - Kapoor, Amit

AU - Simmonds, Peter

AU - Cullen, John M.

AU - Scheel, Troels K.H.

AU - Medina, Jan L.

AU - Giannitti, Federico

AU - Nishiuchi, Eiko

AU - Brock, Kenny V.

AU - Burbelo, Peter D.

AU - Rice, Charles M.

AU - Lipkin, W. Ian

PY - 2013/6

Y1 - 2013/6

N2 - The recent identification of nonprimate hepaciviruses in dogs and then in horses prompted us to look for pegiviruses (GB viruslike viruses) in these species. Although none were detected in canines, we found widespread natural infection of horses by a novel pegivirus. Unique genomic features and phylogenetic analyses confirmed that the tentatively named equine pegivirus (EPgV) represents a novel species within the Pegivirus genus. We also determined that EPgV causes persistent viremia whereas its clinical significance is undetermined.

AB - The recent identification of nonprimate hepaciviruses in dogs and then in horses prompted us to look for pegiviruses (GB viruslike viruses) in these species. Although none were detected in canines, we found widespread natural infection of horses by a novel pegivirus. Unique genomic features and phylogenetic analyses confirmed that the tentatively named equine pegivirus (EPgV) represents a novel species within the Pegivirus genus. We also determined that EPgV causes persistent viremia whereas its clinical significance is undetermined.

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JO - Journal of virology

JF - Journal of virology

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ER -

Identification of a pegivirus (GB virus-like virus) that infects horses

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