Identification of a pegivirus (GB virus-like virus) that infects horses

Amit Kapoor, Peter Simmonds, John M. Cullen, Troels K.H. Scheel, Jan L. Medina, Federico Giannitti, Eiko Nishiuchi, Kenny V. Brock, Peter D. Burbelo, Charles M. Rice, W. Ian Lipkin

Research output: Contribution to journalArticlepeer-review

61 Scopus citations

Abstract

The recent identification of nonprimate hepaciviruses in dogs and then in horses prompted us to look for pegiviruses (GB viruslike viruses) in these species. Although none were detected in canines, we found widespread natural infection of horses by a novel pegivirus. Unique genomic features and phylogenetic analyses confirmed that the tentatively named equine pegivirus (EPgV) represents a novel species within the Pegivirus genus. We also determined that EPgV causes persistent viremia whereas its clinical significance is undetermined.

Original languageEnglish (US)
Pages (from-to)7185-7190
Number of pages6
JournalJournal of virology
Volume87
Issue number12
DOIs
StatePublished - Jun 2013

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