Identification and treatment of metabolic complications in pediatric obesity

Katie Larson Ode, Brigitte I. Frohnert, Brandon M. Nathan

Research output: Contribution to journalReview articlepeer-review

51 Scopus citations


Metabolic consequences of obesity including insulin resistance, type 2 diabetes mellitus, hyperlipidemia, hypertension, polycystic ovarian syndrome, and non-alcoholic fatty liver infiltration are rapidly emerging in the pediatric population. Identifying effective strategies for identifying and treating these obesity related co-morbidities in children are crucial to the prevention of future cardiovascular disease and poor health outcomes. This review discusses the pathophysiologic connections between obesity, metabolic disease and cardiovascular risk. Current evidence and recommendations for screening and treatment for the metabolic consequences of pediatric obesity are reviewed.

Original languageEnglish (US)
Pages (from-to)167-188
Number of pages22
JournalReviews in Endocrine and Metabolic Disorders
Issue number3
StatePublished - Sep 2009


  • Fatty liver disease
  • Insulin resistance
  • Metabolic syndrome
  • Polycystic ovary disease
  • Type 2 diabetes mellitus


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