Identification and characterization of a novel gene disrupted by a pericentric inversion inv(4)(p13.1q21.1) in a family with cleft lip

Keyphrases

• Novel Genes 100%
• Exon 100%
• Pericentric Inversion 100%
• Cleft Lip 100%
• Stearoyl-CoA Desaturase 1 (SCD1) 66%
• Inversion Breakpoints 66%
• Amino Acids 33%
• Drosophila Melanogaster 33%
• Complementary DNA (cDNA) 33%
• Genetic Loci 33%
• Birth Defects 33%
• Expression Level 33%
• Chromosome 4 33%
• Syndromic 33%
• Transmembrane Domain 33%
• Low Expression 33%
• Fluorescence in Situ Hybridization 33%
• Highly Similar 33%
• Bacterial Artificial Chromosome 33%
• Homo Sapiens 33%
• Yeast Artificial Chromosome 33%
• Database Search 33%
• Fetal Liver 33%
• Fetal Lung 33%
• Live Birth 33%
• 4q21 33%
• Fetal Kidney 33%
• Breakpoint Regions 33%
• Adult Tissues 33%
• Cleft Lip with or without Cleft Palate 33%
• Fetal Brain 33%
• Nonsyndromic Clefting 33%
• Desaturase Enzyme 33%
• Histidine Cluster 33%

Biochemistry, Genetics and Molecular Biology

• Exon 100%
• Acyl-CoA 66%
• Amino Acids 33%
• Transmembrane Domain 33%
• Bacterial Artificial Chromosome 33%
• Enzyme 33%
• Drosophila Melanogaster 33%
• Gene Locus 33%
• Molecular Weight 33%
• Fluorescence in Situ Hybridization 33%
• Chromosome 4 33%
• Contig Mapping 33%
• Yeast Artificial Chromosome 33%
• Messenger RNA 33%
• Histidine 33%
• Homo sapiens 33%