Ideal cardiovascular health during adult life and cardiovascular structure and function among the elderly

Amil M. Shah, Brian Claggett, Aaron R. Folsom, Pamela L. Lutsey, Christie M. Ballantyne, Gerardo Heiss, Scott D. Solomon

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Background - A higher American Heart Association cardiovascular health score (CVHS) predicts a lower incidence of cardiovascular disease (CVD). However, the relationship of CVHS attainment through midlife to late life with CVD prevalence and cardiovascular structure and function in late life is not well described. Methods and Results - The following 6 ideal cardiovascular health metrics were assessed in the Atherosclerosis Risk in Communities (ARIC) study participants at 5 examination visits between 1987 and 2013: nonsmoking, body mass index <25 kg/m 2, untreated total cholesterol <200 mg/dL, untreated blood pressure <120/<80 mm Hg, fasting blood glucose <100 mg/dL, and ideal physical activity. Attainment over time was assessed as the percentage of maximum possible CVHS metrics achieved at visits 1 through 5, the slope of change in CVHS per decade of follow-up, and CVHS trajectory through follow-up. At visit 5, participant groups were characterized with respect to CVD prevalence (n=6520) and echocardiographic measures of cardiac structure and function (n=5903 free of CVD). CVHS was low at baseline and declined with age. Both greater CVHS attainment and improvement in CVHS during follow-up were associated with a lower prevalence of CVD and better left ventricular structure and systolic and diastolic function at visit 5. Conclusions - Greater attainment of, and improvements in, ideal cardiovascular health through midlife to late life are associated with lower CVD prevalence and better cardiovascular structure and function when elderly. These findings highlight the importance of consistent primordial and primary prevention efforts throughout midlife to late life as a potential intervention to decrease the burden of CVD among the elderly.

Original languageEnglish (US)
Pages (from-to)1979-1989
Number of pages11
JournalCirculation
Volume132
Issue number21
DOIs
StatePublished - Nov 24 2015

Fingerprint

Cardiovascular Diseases
Health
Primary Prevention
Blood Glucose
Fasting
Atherosclerosis
Body Mass Index
Cholesterol
Exercise
Blood Pressure
Incidence

Keywords

  • aging
  • cardiovascular diseases
  • echocardiography
  • epidemiology
  • risk factors

Cite this

Ideal cardiovascular health during adult life and cardiovascular structure and function among the elderly. / Shah, Amil M.; Claggett, Brian; Folsom, Aaron R.; Lutsey, Pamela L.; Ballantyne, Christie M.; Heiss, Gerardo; Solomon, Scott D.

In: Circulation, Vol. 132, No. 21, 24.11.2015, p. 1979-1989.

Research output: Contribution to journalArticle

Shah, Amil M. ; Claggett, Brian ; Folsom, Aaron R. ; Lutsey, Pamela L. ; Ballantyne, Christie M. ; Heiss, Gerardo ; Solomon, Scott D. / Ideal cardiovascular health during adult life and cardiovascular structure and function among the elderly. In: Circulation. 2015 ; Vol. 132, No. 21. pp. 1979-1989.
@article{8d609258d39f470399caa341d84f61e9,
title = "Ideal cardiovascular health during adult life and cardiovascular structure and function among the elderly",
abstract = "Background - A higher American Heart Association cardiovascular health score (CVHS) predicts a lower incidence of cardiovascular disease (CVD). However, the relationship of CVHS attainment through midlife to late life with CVD prevalence and cardiovascular structure and function in late life is not well described. Methods and Results - The following 6 ideal cardiovascular health metrics were assessed in the Atherosclerosis Risk in Communities (ARIC) study participants at 5 examination visits between 1987 and 2013: nonsmoking, body mass index <25 kg/m 2, untreated total cholesterol <200 mg/dL, untreated blood pressure <120/<80 mm Hg, fasting blood glucose <100 mg/dL, and ideal physical activity. Attainment over time was assessed as the percentage of maximum possible CVHS metrics achieved at visits 1 through 5, the slope of change in CVHS per decade of follow-up, and CVHS trajectory through follow-up. At visit 5, participant groups were characterized with respect to CVD prevalence (n=6520) and echocardiographic measures of cardiac structure and function (n=5903 free of CVD). CVHS was low at baseline and declined with age. Both greater CVHS attainment and improvement in CVHS during follow-up were associated with a lower prevalence of CVD and better left ventricular structure and systolic and diastolic function at visit 5. Conclusions - Greater attainment of, and improvements in, ideal cardiovascular health through midlife to late life are associated with lower CVD prevalence and better cardiovascular structure and function when elderly. These findings highlight the importance of consistent primordial and primary prevention efforts throughout midlife to late life as a potential intervention to decrease the burden of CVD among the elderly.",
keywords = "aging, cardiovascular diseases, echocardiography, epidemiology, risk factors",
author = "Shah, {Amil M.} and Brian Claggett and Folsom, {Aaron R.} and Lutsey, {Pamela L.} and Ballantyne, {Christie M.} and Gerardo Heiss and Solomon, {Scott D.}",
year = "2015",
month = "11",
day = "24",
doi = "10.1161/CIRCULATIONAHA.115.017882",
language = "English (US)",
volume = "132",
pages = "1979--1989",
journal = "Circulation",
issn = "0009-7322",
publisher = "Lippincott Williams and Wilkins",
number = "21",

}

TY - JOUR

T1 - Ideal cardiovascular health during adult life and cardiovascular structure and function among the elderly

AU - Shah, Amil M.

AU - Claggett, Brian

AU - Folsom, Aaron R.

AU - Lutsey, Pamela L.

AU - Ballantyne, Christie M.

AU - Heiss, Gerardo

AU - Solomon, Scott D.

PY - 2015/11/24

Y1 - 2015/11/24

N2 - Background - A higher American Heart Association cardiovascular health score (CVHS) predicts a lower incidence of cardiovascular disease (CVD). However, the relationship of CVHS attainment through midlife to late life with CVD prevalence and cardiovascular structure and function in late life is not well described. Methods and Results - The following 6 ideal cardiovascular health metrics were assessed in the Atherosclerosis Risk in Communities (ARIC) study participants at 5 examination visits between 1987 and 2013: nonsmoking, body mass index <25 kg/m 2, untreated total cholesterol <200 mg/dL, untreated blood pressure <120/<80 mm Hg, fasting blood glucose <100 mg/dL, and ideal physical activity. Attainment over time was assessed as the percentage of maximum possible CVHS metrics achieved at visits 1 through 5, the slope of change in CVHS per decade of follow-up, and CVHS trajectory through follow-up. At visit 5, participant groups were characterized with respect to CVD prevalence (n=6520) and echocardiographic measures of cardiac structure and function (n=5903 free of CVD). CVHS was low at baseline and declined with age. Both greater CVHS attainment and improvement in CVHS during follow-up were associated with a lower prevalence of CVD and better left ventricular structure and systolic and diastolic function at visit 5. Conclusions - Greater attainment of, and improvements in, ideal cardiovascular health through midlife to late life are associated with lower CVD prevalence and better cardiovascular structure and function when elderly. These findings highlight the importance of consistent primordial and primary prevention efforts throughout midlife to late life as a potential intervention to decrease the burden of CVD among the elderly.

AB - Background - A higher American Heart Association cardiovascular health score (CVHS) predicts a lower incidence of cardiovascular disease (CVD). However, the relationship of CVHS attainment through midlife to late life with CVD prevalence and cardiovascular structure and function in late life is not well described. Methods and Results - The following 6 ideal cardiovascular health metrics were assessed in the Atherosclerosis Risk in Communities (ARIC) study participants at 5 examination visits between 1987 and 2013: nonsmoking, body mass index <25 kg/m 2, untreated total cholesterol <200 mg/dL, untreated blood pressure <120/<80 mm Hg, fasting blood glucose <100 mg/dL, and ideal physical activity. Attainment over time was assessed as the percentage of maximum possible CVHS metrics achieved at visits 1 through 5, the slope of change in CVHS per decade of follow-up, and CVHS trajectory through follow-up. At visit 5, participant groups were characterized with respect to CVD prevalence (n=6520) and echocardiographic measures of cardiac structure and function (n=5903 free of CVD). CVHS was low at baseline and declined with age. Both greater CVHS attainment and improvement in CVHS during follow-up were associated with a lower prevalence of CVD and better left ventricular structure and systolic and diastolic function at visit 5. Conclusions - Greater attainment of, and improvements in, ideal cardiovascular health through midlife to late life are associated with lower CVD prevalence and better cardiovascular structure and function when elderly. These findings highlight the importance of consistent primordial and primary prevention efforts throughout midlife to late life as a potential intervention to decrease the burden of CVD among the elderly.

KW - aging

KW - cardiovascular diseases

KW - echocardiography

KW - epidemiology

KW - risk factors

UR - http://www.scopus.com/inward/record.url?scp=84948096748&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84948096748&partnerID=8YFLogxK

U2 - 10.1161/CIRCULATIONAHA.115.017882

DO - 10.1161/CIRCULATIONAHA.115.017882

M3 - Article

VL - 132

SP - 1979

EP - 1989

JO - Circulation

JF - Circulation

SN - 0009-7322

IS - 21

ER -