Hypothyroxinemia in Critically III Patients as a Predictor of High Mortality

Michael F. Slag; John E. Morley; frank q Nuttall; Michael K. Elson; Rex B. Shafer; Terry W. Crowson

doi:10.1001/jama.1981.03310260021020

Hypothyroxinemia in Critically III Patients as a Predictor of High Mortality

Michael F. Slag, John E. Morley, frank q Nuttall, Michael K. Elson, Rex B. Shafer, Terry W. Crowson

Medicine - Veteran's Administration Medical Center

Research output: Contribution to journal › Article › peer-review

86 Scopus citations

Abstract

Thyroid function was measured in 86 patients hospitalized in an intensive care unit. Two patients were found to have primary hypothyroidism and were excluded from the study. Hypothyroxinemia with normal thyroidstimulating hormone (TSH) levels was found in 22% of the patients and was associated with a high mortality (thyroxine [T4] levels less than 3.0 μg/DL, 84% mortality; T4 levels of 3.0 to 5.0 γg/DL, 50% mortality; and T4 levels greater than 5.0 γg/DL, 15% mortality). There was a high correlation between low T4 levels and mortality.

Original language	English (US)
Pages (from-to)	43-45
Number of pages	3
Journal	JAMA: The Journal of the American Medical Association
Volume	245
Issue number	1
DOIs	https://doi.org/10.1001/jama.1981.03310260021020
State	Published - Jan 2 1981

Publisher link

10.1001/jama.1981.03310260021020

Find It

Find It at U of M Libraries

Cite this

@article{858a5e9e317e4cb88ade54577971e91f,

title = "Hypothyroxinemia in Critically III Patients as a Predictor of High Mortality",

abstract = "Thyroid function was measured in 86 patients hospitalized in an intensive care unit. Two patients were found to have primary hypothyroidism and were excluded from the study. Hypothyroxinemia with normal thyroidstimulating hormone (TSH) levels was found in 22% of the patients and was associated with a high mortality (thyroxine [T4] levels less than 3.0 μg/DL, 84% mortality; T4 levels of 3.0 to 5.0 γg/DL, 50% mortality; and T4 levels greater than 5.0 γg/DL, 15% mortality). There was a high correlation between low T4 levels and mortality.",

author = "Slag, {Michael F.} and Morley, {John E.} and Nuttall, {frank q} and Elson, {Michael K.} and Shafer, {Rex B.} and Crowson, {Terry W.}",

year = "1981",

month = jan,

day = "2",

doi = "10.1001/jama.1981.03310260021020",

language = "English (US)",

volume = "245",

pages = "43--45",

journal = "JAMA: The Journal of the American Medical Association",

issn = "0098-7484",

publisher = "American Medical Association",

number = "1",

}

TY - JOUR

T1 - Hypothyroxinemia in Critically III Patients as a Predictor of High Mortality

AU - Slag, Michael F.

AU - Morley, John E.

AU - Nuttall, frank q

AU - Elson, Michael K.

AU - Shafer, Rex B.

AU - Crowson, Terry W.

PY - 1981/1/2

Y1 - 1981/1/2

N2 - Thyroid function was measured in 86 patients hospitalized in an intensive care unit. Two patients were found to have primary hypothyroidism and were excluded from the study. Hypothyroxinemia with normal thyroidstimulating hormone (TSH) levels was found in 22% of the patients and was associated with a high mortality (thyroxine [T4] levels less than 3.0 μg/DL, 84% mortality; T4 levels of 3.0 to 5.0 γg/DL, 50% mortality; and T4 levels greater than 5.0 γg/DL, 15% mortality). There was a high correlation between low T4 levels and mortality.

AB - Thyroid function was measured in 86 patients hospitalized in an intensive care unit. Two patients were found to have primary hypothyroidism and were excluded from the study. Hypothyroxinemia with normal thyroidstimulating hormone (TSH) levels was found in 22% of the patients and was associated with a high mortality (thyroxine [T4] levels less than 3.0 μg/DL, 84% mortality; T4 levels of 3.0 to 5.0 γg/DL, 50% mortality; and T4 levels greater than 5.0 γg/DL, 15% mortality). There was a high correlation between low T4 levels and mortality.

UR - http://www.scopus.com/inward/record.url?scp=84948722591&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84948722591&partnerID=8YFLogxK

U2 - 10.1001/jama.1981.03310260021020

DO - 10.1001/jama.1981.03310260021020

M3 - Article

AN - SCOPUS:84948722591

SN - 0098-7484

VL - 245

SP - 43

EP - 45

JO - JAMA: The Journal of the American Medical Association

JF - JAMA: The Journal of the American Medical Association

IS - 1

ER -

Hypothyroxinemia in Critically III Patients as a Predictor of High Mortality

Abstract

Publisher link

Find It

Other files and links

Fingerprint

Cite this