Abstract
An efficient synthetic procedure for di-cyano-cyclopropanation of alkenes using catalytic amounts of molecular iodine as a precatalyst and tert-butyl hydroperoxide (TBHP) as a terminal oxidant under mild conditions has been developed. This catalytic reaction works especially well for the aryl-substituted double bond affording products of cyclopropanation in high yields. A catalytic cycle based on the generated in situ hypoiodite species has been proposed,.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 3336-3340 |
| Number of pages | 5 |
| Journal | Advanced Synthesis and Catalysis |
| Volume | 356 |
| Issue number | 16 |
| DOIs | |
| State | Published - Sep 21 2014 |
Bibliographical note
Publisher Copyright:©2014 Wiley-VCH Verlag GmbH&Co. KGaA, Weinheim.
Keywords
- Cyclopropanation
- Hypoiodite
- Iodine
- Organocatalysis
- Oxidation