Hypoglycemia in diabetes: The dark side of diabetes treatment. A patient-centered review

Translated title of the contribution: Hypoglycemia in diabetes: The dark side of diabetes treatment. A patient-centered review

Brianna Johnson-Rabbett, Elizabeth R. Seaquist

Research output: Contribution to journalReview articlepeer-review

23 Scopus citations

Abstract

Hypoglycemia is a frequent occurrence in patients with diabetes who are treated with insulin and insulin secretagogues. Hypoglycemia is the limiting factor that prevents patients from achieving the glycemic control known to reduce the microvascular complications of diabetes. Recurrent episodes of hypoglycemia can lead to impaired awareness of hypoglycemia where the first symptom of a low blood sugar is unconsciousness. The fear of hypoglycemia has a significant effect on the quality of life of patients and their families. In the acute setting, hypoglycemia can kill, and clinical trials have demonstrated that a single episode of severe hypoglycemia increases the risk of subsequent mortality and cardiovascular events. Clinicians must make efforts to recognize and prevent hypoglycemia in order to prevent the adverse events associated with this event. Patient education is central to these efforts. Recent developments in glucose monitoring and drug development have provided more approaches that can be used to reduce the risk of hypoglycemia in patients with diabetes.

Translated title of the contributionHypoglycemia in diabetes: The dark side of diabetes treatment. A patient-centered review
Original languageChinese (Traditional)
Pages (from-to)711-718
Number of pages8
JournalJournal of Diabetes
Volume11
Issue number9
DOIs
StatePublished - 2019

Bibliographical note

Funding Information:
BJ‐R declares no conflict of interest. ERS has previously consulted for Sanofi, Lilly, and Zucara, her institution has received grant funding from Lilly for her research, and she is a member of the International Hypoglycemia Study Group that is supported by an unrestricted grant from Novo Nordisk.

Publisher Copyright:
© 2019 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and John Wiley & Sons Australia, Ltd

Keywords

  • cardiovascular disease
  • diabetes
  • hypoglycemia
  • insulin
  • mortality

PubMed: MeSH publication types

  • Review
  • Journal Article

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