Hypoglycemia in cystic fibrosis: Prevalence, impact and treatment

Amir Moheet, Christine L. Chan, Andrea Granados, Katie Larson Ode, Antoinette Moran, Alberto Battezzati

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Hypoglycemia is a common and feared complication of insulin therapy. As in type 1 and type 2 diabetes, people with cystic fibrosis related diabetes are also at risk for hypoglycemia related to insulin therapy. Spontaneous hypoglycemia is also common in patients with CF without diabetes, who are not on glucose lowering medications. Spontaneous hypoglycemia in CF may also occur during or after an oral glucose tolerance test. In this review, we will discuss the definition, epidemiology, pathophysiology and impact of hypoglycemia, with a focus on people with cystic fibrosis. We will also review strategies to manage and prevent hypoglycemia.

Original languageEnglish (US)
Pages (from-to)S19-S24
JournalJournal of Cystic Fibrosis
StatePublished - Oct 2019

Bibliographical note

Funding Information:
AAM, CLC, AG, KLO and AM received grant support through the Cystic Fibrosis Foundation , Emerging Leaders in CF Endocrinology (EnVision) Program. The authors would like to thank the Cystic Fibrosis Foundation and the faculty mentor members of the EnVision Program , for their ongoing support and mentorship of the program awardees.

Publisher Copyright:
© 2019 European Cystic Fibrosis Society


  • CFRD
  • Cystic fibrosis
  • Hypoglycemia
  • Reactive hypoglycemia

PubMed: MeSH publication types

  • Journal Article
  • Research Support, Non-U.S. Gov't
  • Review


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