Hypoglycaemia in type 1 diabetes mellitus: risks and practical prevention strategies

Jasleen Kaur, Elizabeth R. Seaquist

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


Hypoglycaemia, which occurs when blood levels of glucose fall below what is considered a normal range, is a well-known complication of insulin therapy in individuals with type 1 diabetes mellitus. Despite advances in diabetes mellitus management, hypoglycaemia has continued to affect the majority of these individuals, leading to suboptimal care and decreased quality of life. Multiple epidemiological studies have demonstrated the risks associated with hypoglycaemic events. With this understanding, various advances have been made in therapeutics for diabetes mellitus management. Diabetes mellitus education continues to form the foundation for management and prevention of hypoglycaemia. The advent of newer diabetes mellitus technologies and newer insulins herald improvements in management strategies and hypoglycaemia prevention. Improved understanding of these newer approaches is needed to ensure delivery of safe and effective care to individuals with type 1 diabetes mellitus, leading to reductions in both the short-term and long-term morbidity and mortality associated with hypoglycaemic events.

Original languageEnglish (US)
Pages (from-to)177-186
Number of pages10
JournalNature Reviews Endocrinology
Issue number3
StatePublished - Mar 2023

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© 2022, Springer Nature Limited.


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