Hypocellular acute leukemia

Robert B. Howe; Clara D. Bloomfield; Robert W. McKenna

doi:10.1016/0002-9343(82)90494-6

Hypocellular acute leukemia

Robert B. Howe, Clara D. Bloomfield, Robert W. McKenna

Laboratory Medicine and Pathology

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

We examined the clinical features and therapeutic response of a group of patients with acute leukemia and hypocellular bone marrow. Therapists have generally avoided, delayed or modified therapy because of hypocellularity. We demonstrated not only that aggressive therapy is possible, but also that the remission rate is high (complete remission = 73 percent) and survival prolonged (x̄ > 40 months).

Original language	English (US)
Pages (from-to)	391-395
Number of pages	5
Journal	The American Journal of Medicine
Volume	72
Issue number	3
DOIs	https://doi.org/10.1016/0002-9343(82)90494-6
State	Published - Mar 1982

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title = "Hypocellular acute leukemia",

abstract = "We examined the clinical features and therapeutic response of a group of patients with acute leukemia and hypocellular bone marrow. Therapists have generally avoided, delayed or modified therapy because of hypocellularity. We demonstrated not only that aggressive therapy is possible, but also that the remission rate is high (complete remission = 73 percent) and survival prolonged ({\=x} > 40 months).",

author = "Howe, {Robert B.} and Bloomfield, {Clara D.} and McKenna, {Robert W.}",

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AU - McKenna, Robert W.

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N2 - We examined the clinical features and therapeutic response of a group of patients with acute leukemia and hypocellular bone marrow. Therapists have generally avoided, delayed or modified therapy because of hypocellularity. We demonstrated not only that aggressive therapy is possible, but also that the remission rate is high (complete remission = 73 percent) and survival prolonged (x̄ > 40 months).

AB - We examined the clinical features and therapeutic response of a group of patients with acute leukemia and hypocellular bone marrow. Therapists have generally avoided, delayed or modified therapy because of hypocellularity. We demonstrated not only that aggressive therapy is possible, but also that the remission rate is high (complete remission = 73 percent) and survival prolonged (x̄ > 40 months).

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