Hypersensitivity reactions to titanium: diagnosis and management

Megan M. Wood, Erin M. Warshaw

Research output: Contribution to journalReview articlepeer-review

51 Scopus citations


Titanium is notable for its biocompatibility and is used as biologic implant material across surgical specialties, especially in metal-sensitive individuals. However, rare cases of titanium hypersensitivity reactions are reported in the literature. This article discusses the properties and biological behavior of titanium and provides a thorough review of the literature on reported cases, diagnostic techniques, and approach to management of titanium hypersensitivity.

Original languageEnglish (US)
Pages (from-to)7-25
Number of pages19
JournalDermatitis : contact, atopic, occupational, drug
Issue number1
StatePublished - Jan 1 2015

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© 2014 American Contact Dermatitis Society. All Rights Reserved.


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