Hyperlipidemia in kidney disease: Causes and consequences

Meena Sahadevan, Bertram L. Kasiske

Research output: Contribution to journalReview articlepeer-review

29 Scopus citations

Abstract

Dyslipidemias are common in patients with chronic kidney disease. The causes vary with the stage of kidney disease, the degree of proteinuria, and the modality of end-stage renal disease treatment. Dyslipidemias have been associated with kidney disease progression, and a number of small, randomized, controlled trials of lipid-lowering agents have been conducted. Unfortunately, the results of these trials, although encouraging, have been inconclusive because of the small numbers of patients enrolled. Dyslipidemias may also contribute to the high incidence of cardiovascular disease in patients with chronic kidney disease. This is most likely for patients with chronic renal insufficiency and for kidney transplant recipients. Less certain is the role of dyslipidemias in the pathogenesis of cardiovascular disease among dialysis patients.

Original languageEnglish (US)
Pages (from-to)323-329
Number of pages7
JournalCurrent opinion in nephrology and hypertension
Volume11
Issue number3
DOIs
StatePublished - May 21 2002

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