Abstract
Erythrovirus B19 (B19V) is a member of the family Parvoviridae. Infection with B19V has been linked to a variety of diseases including erythroid, thyroid, neurological and autoimmune diseases. Here we show that infection of primary CD36+ cells with B19V coincides with downregulation of thyroid, retinoid, and estrogen hormone receptors. In addition we show changes in expression of a variety of related downstream signaling genes participating in cancer and cardiac-related diseases in B19V-infected erythroid primary cells.
Original language | English (US) |
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Pages (from-to) | 173-179 |
Number of pages | 7 |
Journal | Virology |
Volume | 446 |
Issue number | 1-2 |
DOIs | |
State | Published - Nov 2013 |
Keywords
- Erythroid
- Erythrovirus
- Estrogen
- Hormone
- Hormone receptor
- Nuclear receptor
- Parvovirus
- Retinoid
- Thyroid