TY - JOUR
T1 - How can clinical studies and large-scale intervention trials help optimise individually targeted therapy
AU - Cohn, Jay N.
PY - 1997
Y1 - 1997
N2 - Large-scale clinical trials of hypertensive therapy recruit patients with elevated blood pressure and aim, long term, to reduce the incidence of associated cardiovascular events (usually myocardial infarctions, symptomatic coronary disease, strokes and death). Although this approach is currently mandatory for demonstrating the efficacy of blood pressure-reducing drugs on outcomes, it has a number of drawbacks. This manuscript explores them.
AB - Large-scale clinical trials of hypertensive therapy recruit patients with elevated blood pressure and aim, long term, to reduce the incidence of associated cardiovascular events (usually myocardial infarctions, symptomatic coronary disease, strokes and death). Although this approach is currently mandatory for demonstrating the efficacy of blood pressure-reducing drugs on outcomes, it has a number of drawbacks. This manuscript explores them.
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M3 - Article
SN - 1368-504X
SP - 74
EP - 75
JO - International Journal of Clinical Practice, Supplement
JF - International Journal of Clinical Practice, Supplement
IS - SUPPL. 92
ER -
