Host-Mycobacterium avium subsp. paratuberculosis interactome reveals a novel iron assimilation mechanism linked to nitric oxide stress during early infection

Keyphrases

• Mycobacterium Avium 100%
• Paratuberculosis 100%
• Interactome 100%
• Early Infection 100%
• Iron Assimilation 100%
• Nitric Oxide Stress 100%
• Nitric Oxide 40%
• Host Cell 40%
• Iron Sequestration 40%
• Co-culture System 40%
• Novel Therapeutic Targets 20%
• Metabolic 20%
• Macrophages 20%
• Co-host 20%
• Disease Course 20%
• Epithelial Cells 20%
• Mycobactin 20%
• Inflammatory Pathways 20%
• Epithelium 20%
• Long-term Survival 20%
• Initial Interactions 20%
• RNA Sequencing (RNA-seq) 20%
• Virulence Genes 20%
• Enteric Pathogens 20%
• DNA Repair Genes 20%
• Iron Limitation 20%
• Pathogenesis Studies 20%
• NOS2 20%
• Host-pathogen 20%
• Bovine Macrophages 20%
• Hypothesis-driven Research 20%
• MAC-T 20%
• Carboxymycobactin 20%
• Assimilation System 20%
• Tolerant Genotypes 20%

Immunology and Microbiology

• Infectious Disease 100%
• Mycobacterium avium 100%
• Infection 100%
• Infectious Agent 75%
• Coculture 75%
• Macrophage 50%
• Host Cell 50%
• Nitric Oxide Synthase 2 25%
• RNA Sequencing 25%
• Epithelium 25%
• down Regulation 25%
• Long Term Survival 25%
• DNA Repair 25%
• In Vitro 25%

Biochemistry, Genetics and Molecular Biology

• Interactome 100%
• Nitric Oxide 100%
• Mycobacterium avium 100%
• Infectious Agent 60%
• Coculture 60%
• Macrophage 40%
• Genotyping 20%
• RNA Sequencing 20%
• Virulence Gene 20%
• DNA Repair 20%
• down Regulation 20%
• Long Term Survival 20%
• Nitric Oxide Synthase 20%