Hospital admission for acute painful episode following methacholine challenge in an adolescent with sickle cell disease

Jessica E. Knight-Perry, Joshua J. Field, Michael R. DeBaun, Janet Stocks, Jane Kirkby, Robert C. Strunk

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Asthma is associated with increases in sickle cell disease (SCD)-related morbidityand mortality. A thorough evaluation for asthma in children with SCD is important and may involve methacholine challenge (MCh). In this report, we present a 14-year-old male with SCD who was admitted for an acute painful episode following MCh. Pain events after MCh have not been previously reported in children with SCD. The risk-benefit ratio should be strongly considered prior to performance of MCh in this patient population, and all possible complications, including an acute painful episode, should be openly discussed with the parents and pediatric patient.

Original languageEnglish (US)
Pages (from-to)728-730
Number of pages3
JournalPediatric pulmonology
Volume44
Issue number7
DOIs
StatePublished - Jul 2009

Keywords

  • Asthma
  • Methacholine challenge
  • Pain
  • Sickle cell disease

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