Hormone Replacement and Cardiovascular Risk Factors

Barnett Zumoff; David Crook; John C. Stevenson; J. C. Daubresse; Avrum Z. Bluming; Azmi A. Nabulsi; Aaron R. Folsom; Alice White; Kathryn A. Martin; Mason W. Freeman

doi:10.1056/NEJM199309303291415

Hormone Replacement and Cardiovascular Risk Factors

Barnett Zumoff, David Crook, John C. Stevenson, J. C. Daubresse, Avrum Z. Bluming, Azmi A. Nabulsi, Aaron R. Folsom, Alice White, Kathryn A. Martin, Mason W. Freeman

Epidemiology & Community Health

Research output: Contribution to journal › Letter › peer-review

6 Scopus citations

Abstract

To the Editor: Nabulsi et al. (April 15 issue)¹ present convincing data that postmenopausal hormone-replacement therapy, whether with estrogen alone or with estrogen and progestin, greatly decreases the risk of cardiovascular disease. In their editorial, Martin and Freeman reiterate what has become almost conventional wisdom – namely, that replacement therapy with progestins “attenuates [the] beneficial effects of estrogen on lipid levels” and therefore, presumably, may weaken the protective effect of estrogen-replacement therapy against cardiovascular disease². I should like to cite a number of studies that offer reassurance that progestins probably do not have such a deleterious effect. Two recent…

Original language	English (US)
Pages (from-to)	1041-1043
Number of pages	3
Journal	New England Journal of Medicine
Volume	329
Issue number	14
DOIs	https://doi.org/10.1056/NEJM199309303291415
State	Published - Sep 30 1993

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title = "Hormone Replacement and Cardiovascular Risk Factors",

abstract = "To the Editor: Nabulsi et al. (April 15 issue)1 present convincing data that postmenopausal hormone-replacement therapy, whether with estrogen alone or with estrogen and progestin, greatly decreases the risk of cardiovascular disease. In their editorial, Martin and Freeman reiterate what has become almost conventional wisdom – namely, that replacement therapy with progestins “attenuates [the] beneficial effects of estrogen on lipid levels” and therefore, presumably, may weaken the protective effect of estrogen-replacement therapy against cardiovascular disease2. I should like to cite a number of studies that offer reassurance that progestins probably do not have such a deleterious effect. Two recent…",

author = "Barnett Zumoff and David Crook and Stevenson, {John C.} and Daubresse, {J. C.} and Bluming, {Avrum Z.} and Nabulsi, {Azmi A.} and Folsom, {Aaron R.} and Alice White and Martin, {Kathryn A.} and Freeman, {Mason W.}",

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TY - JOUR

T1 - Hormone Replacement and Cardiovascular Risk Factors

AU - Zumoff, Barnett

AU - Crook, David

AU - Stevenson, John C.

AU - Daubresse, J. C.

AU - Bluming, Avrum Z.

AU - Nabulsi, Azmi A.

AU - Folsom, Aaron R.

AU - White, Alice

AU - Martin, Kathryn A.

AU - Freeman, Mason W.

PY - 1993/9/30

Y1 - 1993/9/30

N2 - To the Editor: Nabulsi et al. (April 15 issue)1 present convincing data that postmenopausal hormone-replacement therapy, whether with estrogen alone or with estrogen and progestin, greatly decreases the risk of cardiovascular disease. In their editorial, Martin and Freeman reiterate what has become almost conventional wisdom – namely, that replacement therapy with progestins “attenuates [the] beneficial effects of estrogen on lipid levels” and therefore, presumably, may weaken the protective effect of estrogen-replacement therapy against cardiovascular disease2. I should like to cite a number of studies that offer reassurance that progestins probably do not have such a deleterious effect. Two recent…

AB - To the Editor: Nabulsi et al. (April 15 issue)1 present convincing data that postmenopausal hormone-replacement therapy, whether with estrogen alone or with estrogen and progestin, greatly decreases the risk of cardiovascular disease. In their editorial, Martin and Freeman reiterate what has become almost conventional wisdom – namely, that replacement therapy with progestins “attenuates [the] beneficial effects of estrogen on lipid levels” and therefore, presumably, may weaken the protective effect of estrogen-replacement therapy against cardiovascular disease2. I should like to cite a number of studies that offer reassurance that progestins probably do not have such a deleterious effect. Two recent…

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M3 - Letter

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Hormone Replacement and Cardiovascular Risk Factors

Abstract

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