Abstract
The requirements for T-cell proliferation driven by "space-filling" (homeostatic expansion) differ significantly from those for antigen-driven responses. Here we review these differences and discuss their implications for regulation of T-cell responses and the size of the T-cell compartment.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 531-537 |
| Number of pages | 7 |
| Journal | Microbes and Infection |
| Volume | 4 |
| Issue number | 5 |
| DOIs | |
| State | Published - 2002 |
Keywords
- Costimulation
- Cytokine
- Expansion
- Homeostasis
- Lymphopenia
- Proliferation
- Survival
- T cell
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