Homeostatic expansion versus antigen-driven proliferation: Common ends by different means?

Martin Prlic, Stephen C. Jameson

Research output: Contribution to journalReview articlepeer-review

33 Scopus citations

Abstract

The requirements for T-cell proliferation driven by "space-filling" (homeostatic expansion) differ significantly from those for antigen-driven responses. Here we review these differences and discuss their implications for regulation of T-cell responses and the size of the T-cell compartment.

Original languageEnglish (US)
Pages (from-to)531-537
Number of pages7
JournalMicrobes and Infection
Volume4
Issue number5
DOIs
StatePublished - Apr 25 2002

Keywords

  • Costimulation
  • Cytokine
  • Expansion
  • Homeostasis
  • Lymphopenia
  • Proliferation
  • Survival
  • T cell

Fingerprint Dive into the research topics of 'Homeostatic expansion versus antigen-driven proliferation: Common ends by different means?'. Together they form a unique fingerprint.

Cite this