Homeostatic expansion versus antigen-driven proliferation: Common ends by different means?

Martin Prlic; Stephen C. Jameson

doi:10.1016/S1286-4579(02)01569-1

Homeostatic expansion versus antigen-driven proliferation: Common ends by different means?

Martin Prlic, Stephen C. Jameson

Laboratory Medicine and Pathology

Research output: Contribution to journal › Review article › peer-review

33 Scopus citations

Abstract

The requirements for T-cell proliferation driven by "space-filling" (homeostatic expansion) differ significantly from those for antigen-driven responses. Here we review these differences and discuss their implications for regulation of T-cell responses and the size of the T-cell compartment.

Original language	English (US)
Pages (from-to)	531-537
Number of pages	7
Journal	Microbes and Infection
Volume	4
Issue number	5
DOIs	https://doi.org/10.1016/S1286-4579(02)01569-1
State	Published - Apr 25 2002

Keywords

Costimulation
Cytokine
Expansion
Homeostasis
Lymphopenia
Proliferation
Survival
T cell

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S1286-4579(02)01569-1

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title = "Homeostatic expansion versus antigen-driven proliferation: Common ends by different means?",

abstract = "The requirements for T-cell proliferation driven by {"}space-filling{"} (homeostatic expansion) differ significantly from those for antigen-driven responses. Here we review these differences and discuss their implications for regulation of T-cell responses and the size of the T-cell compartment.",

keywords = "Costimulation, Cytokine, Expansion, Homeostasis, Lymphopenia, Proliferation, Survival, T cell",

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T1 - Homeostatic expansion versus antigen-driven proliferation

T2 - Common ends by different means?

AU - Prlic, Martin

AU - Jameson, Stephen C.

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N2 - The requirements for T-cell proliferation driven by "space-filling" (homeostatic expansion) differ significantly from those for antigen-driven responses. Here we review these differences and discuss their implications for regulation of T-cell responses and the size of the T-cell compartment.

AB - The requirements for T-cell proliferation driven by "space-filling" (homeostatic expansion) differ significantly from those for antigen-driven responses. Here we review these differences and discuss their implications for regulation of T-cell responses and the size of the T-cell compartment.

KW - Costimulation

KW - Cytokine

KW - Expansion

KW - Homeostasis

KW - Lymphopenia

KW - Proliferation

KW - Survival

KW - T cell

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U2 - 10.1016/S1286-4579(02)01569-1

DO - 10.1016/S1286-4579(02)01569-1

M3 - Review article

C2 - 11959508

AN - SCOPUS:0036226877

SN - 1286-4579

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EP - 537

JO - Microbes and Infection

JF - Microbes and Infection

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ER -

Homeostatic expansion versus antigen-driven proliferation: Common ends by different means?

Abstract

Keywords

UN SDGs

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