HIV incidence, retention rate, and baseline predictors of HIV incidence and retention in a prospective cohort study of injection drug users in Xinjiang, China

Yuanzhi Zhang; Hua Shan; Jennifer Trizzino; Yuhua Ruan; Geetha Beauchamp; Benoît Mâsse; Jun Ma; Baoling Rui; Jun Wang; Minsheng Liu; Yunxia Wang; Yixin He; Katharine Poundstone; Yan Jiang; J. Brooks Jackson; Yiming Shao

doi:10.1016/j.ijid.2006.09.001

HIV incidence, retention rate, and baseline predictors of HIV incidence and retention in a prospective cohort study of injection drug users in Xinjiang, China

Yuanzhi Zhang, Hua Shan, Jennifer Trizzino, Yuhua Ruan, Geetha Beauchamp, Benoît Mâsse, Jun Ma, Baoling Rui, Jun Wang, Minsheng Liu, Yunxia Wang, Yixin He, Katharine Poundstone, Yan Jiang, J. Brooks Jackson, Yiming Shao

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

Objective: To determine HIV seroincidence, study participant retention rate, and baseline predictors of HIV incidence and study retention among high-risk injection drug users (IDUs) in Xinjiang, China. Methods: A total of 508 eligible seronegative high-risk IDUs were enrolled. Study participants were tested for HIV-1 and counseled at the baseline, 6-month, and 12-month follow-up visits. Sociodemographic and behavioral data were collected during each study visit. The HIV-1 incidence rate and the retention rate were analyzed as a function of sociodemographic, behavioral, and recruitment variables. Results: At 12 months of follow-up, the HIV-1 incidence rate was 8.8 per 100 person-years (95% CI 6.3-12.0%) and the participant retention rate was 93%. Marital status at baseline was the only predictor of HIV incidence. No baseline variables were predictive of study retention. Conclusions: HIV incidence is high among IDUs in Xinjiang, China. Baseline predictors of incidence and retention were minimal. The participant retention rate in this study is promising for the undertaking of future HIV intervention studies.

Original language	English (US)
Pages (from-to)	318-323
Number of pages	6
Journal	International Journal of Infectious Diseases
Volume	11
Issue number	4
DOIs	https://doi.org/10.1016/j.ijid.2006.09.001
State	Published - Jul 2007
Externally published	Yes

Bibliographical note

Funding Information:
The investigators are grateful to the men and women who participated in this study. Special thanks are offered to Shao Hua Wang, Ai Hua Zhang, Jing Gong Hao, Mawlan Mamtimin, Parhat Yadikar, Yongsheng Guan, Minawar Abai, Chun Mei Zhao, Xahadetgul Sulayman, Jing Wang, Gulsum Ghuja, Ben Lai Liu, Abdurahman, Jun Wei, Abdurixit, Dongbao Yu, and Yun Xia Wang. The authors would like to acknowledge support from the Xinjiang Bureau of Health, Deborah Hilgenberg of Family Health International, the Urumqi Detoxification Center, and the Xinjiang Public Security Bureau.

Funding Information:
Sponsorship: This study was supported by the National Center for HIV/AIDS Prevention and Control of the Chinese Center for Disease Control and Prevention (China CDC), the Xinjiang Uighur Autonomous Region CDC, the Urumqi Municipal CDC, and by the National Institute of Allergy and Infectious Disease, the National Institute of Drug Abuse, the National Institute of Child Health and Development, and the National Institute of Mental Health, United States National Institutes of Health through the HIV Prevention Trials Network (U01-A0-48011).

Keywords

China
HIV
IDUs
Incidence
Retention
Xinjiang

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.ijid.2006.09.001

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Zhang, Y., Shan, H., Trizzino, J., Ruan, Y., Beauchamp, G., Mâsse, B., Ma, J., Rui, B., Wang, J., Liu, M., Wang, Y., He, Y., Poundstone, K., Jiang, Y., Jackson, J. B., & Shao, Y. (2007). HIV incidence, retention rate, and baseline predictors of HIV incidence and retention in a prospective cohort study of injection drug users in Xinjiang, China. International Journal of Infectious Diseases, 11(4), 318-323. https://doi.org/10.1016/j.ijid.2006.09.001

Zhang, Y, Shan, H, Trizzino, J, Ruan, Y, Beauchamp, G, Mâsse, B, Ma, J, Rui, B, Wang, J, Liu, M, Wang, Y, He, Y, Poundstone, K, Jiang, Y, Jackson, JB & Shao, Y 2007, 'HIV incidence, retention rate, and baseline predictors of HIV incidence and retention in a prospective cohort study of injection drug users in Xinjiang, China', International Journal of Infectious Diseases, vol. 11, no. 4, pp. 318-323. https://doi.org/10.1016/j.ijid.2006.09.001

@article{799a4f60fbf64836a59df60f45af9fb2,

title = "HIV incidence, retention rate, and baseline predictors of HIV incidence and retention in a prospective cohort study of injection drug users in Xinjiang, China",

abstract = "Objective: To determine HIV seroincidence, study participant retention rate, and baseline predictors of HIV incidence and study retention among high-risk injection drug users (IDUs) in Xinjiang, China. Methods: A total of 508 eligible seronegative high-risk IDUs were enrolled. Study participants were tested for HIV-1 and counseled at the baseline, 6-month, and 12-month follow-up visits. Sociodemographic and behavioral data were collected during each study visit. The HIV-1 incidence rate and the retention rate were analyzed as a function of sociodemographic, behavioral, and recruitment variables. Results: At 12 months of follow-up, the HIV-1 incidence rate was 8.8 per 100 person-years (95% CI 6.3-12.0%) and the participant retention rate was 93%. Marital status at baseline was the only predictor of HIV incidence. No baseline variables were predictive of study retention. Conclusions: HIV incidence is high among IDUs in Xinjiang, China. Baseline predictors of incidence and retention were minimal. The participant retention rate in this study is promising for the undertaking of future HIV intervention studies.",

keywords = "China, HIV, IDUs, Incidence, Retention, Xinjiang",

author = "Yuanzhi Zhang and Hua Shan and Jennifer Trizzino and Yuhua Ruan and Geetha Beauchamp and Beno{\^i}t M{\^a}sse and Jun Ma and Baoling Rui and Jun Wang and Minsheng Liu and Yunxia Wang and Yixin He and Katharine Poundstone and Yan Jiang and Jackson, {J. Brooks} and Yiming Shao",

note = "Funding Information: The investigators are grateful to the men and women who participated in this study. Special thanks are offered to Shao Hua Wang, Ai Hua Zhang, Jing Gong Hao, Mawlan Mamtimin, Parhat Yadikar, Yongsheng Guan, Minawar Abai, Chun Mei Zhao, Xahadetgul Sulayman, Jing Wang, Gulsum Ghuja, Ben Lai Liu, Abdurahman, Jun Wei, Abdurixit, Dongbao Yu, and Yun Xia Wang. The authors would like to acknowledge support from the Xinjiang Bureau of Health, Deborah Hilgenberg of Family Health International, the Urumqi Detoxification Center, and the Xinjiang Public Security Bureau. Funding Information: Sponsorship: This study was supported by the National Center for HIV/AIDS Prevention and Control of the Chinese Center for Disease Control and Prevention (China CDC), the Xinjiang Uighur Autonomous Region CDC, the Urumqi Municipal CDC, and by the National Institute of Allergy and Infectious Disease, the National Institute of Drug Abuse, the National Institute of Child Health and Development, and the National Institute of Mental Health, United States National Institutes of Health through the HIV Prevention Trials Network (U01-A0-48011). ",

year = "2007",

month = jul,

doi = "10.1016/j.ijid.2006.09.001",

language = "English (US)",

volume = "11",

pages = "318--323",

journal = "International Journal of Infectious Diseases",

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publisher = "Elsevier",

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TY - JOUR

T1 - HIV incidence, retention rate, and baseline predictors of HIV incidence and retention in a prospective cohort study of injection drug users in Xinjiang, China

AU - Zhang, Yuanzhi

AU - Shan, Hua

AU - Trizzino, Jennifer

AU - Ruan, Yuhua

AU - Beauchamp, Geetha

AU - Mâsse, Benoît

AU - Ma, Jun

AU - Rui, Baoling

AU - Wang, Jun

AU - Liu, Minsheng

AU - Wang, Yunxia

AU - He, Yixin

AU - Poundstone, Katharine

AU - Jiang, Yan

AU - Jackson, J. Brooks

AU - Shao, Yiming

N1 - Funding Information: The investigators are grateful to the men and women who participated in this study. Special thanks are offered to Shao Hua Wang, Ai Hua Zhang, Jing Gong Hao, Mawlan Mamtimin, Parhat Yadikar, Yongsheng Guan, Minawar Abai, Chun Mei Zhao, Xahadetgul Sulayman, Jing Wang, Gulsum Ghuja, Ben Lai Liu, Abdurahman, Jun Wei, Abdurixit, Dongbao Yu, and Yun Xia Wang. The authors would like to acknowledge support from the Xinjiang Bureau of Health, Deborah Hilgenberg of Family Health International, the Urumqi Detoxification Center, and the Xinjiang Public Security Bureau. Funding Information: Sponsorship: This study was supported by the National Center for HIV/AIDS Prevention and Control of the Chinese Center for Disease Control and Prevention (China CDC), the Xinjiang Uighur Autonomous Region CDC, the Urumqi Municipal CDC, and by the National Institute of Allergy and Infectious Disease, the National Institute of Drug Abuse, the National Institute of Child Health and Development, and the National Institute of Mental Health, United States National Institutes of Health through the HIV Prevention Trials Network (U01-A0-48011).

PY - 2007/7

Y1 - 2007/7

N2 - Objective: To determine HIV seroincidence, study participant retention rate, and baseline predictors of HIV incidence and study retention among high-risk injection drug users (IDUs) in Xinjiang, China. Methods: A total of 508 eligible seronegative high-risk IDUs were enrolled. Study participants were tested for HIV-1 and counseled at the baseline, 6-month, and 12-month follow-up visits. Sociodemographic and behavioral data were collected during each study visit. The HIV-1 incidence rate and the retention rate were analyzed as a function of sociodemographic, behavioral, and recruitment variables. Results: At 12 months of follow-up, the HIV-1 incidence rate was 8.8 per 100 person-years (95% CI 6.3-12.0%) and the participant retention rate was 93%. Marital status at baseline was the only predictor of HIV incidence. No baseline variables were predictive of study retention. Conclusions: HIV incidence is high among IDUs in Xinjiang, China. Baseline predictors of incidence and retention were minimal. The participant retention rate in this study is promising for the undertaking of future HIV intervention studies.

AB - Objective: To determine HIV seroincidence, study participant retention rate, and baseline predictors of HIV incidence and study retention among high-risk injection drug users (IDUs) in Xinjiang, China. Methods: A total of 508 eligible seronegative high-risk IDUs were enrolled. Study participants were tested for HIV-1 and counseled at the baseline, 6-month, and 12-month follow-up visits. Sociodemographic and behavioral data were collected during each study visit. The HIV-1 incidence rate and the retention rate were analyzed as a function of sociodemographic, behavioral, and recruitment variables. Results: At 12 months of follow-up, the HIV-1 incidence rate was 8.8 per 100 person-years (95% CI 6.3-12.0%) and the participant retention rate was 93%. Marital status at baseline was the only predictor of HIV incidence. No baseline variables were predictive of study retention. Conclusions: HIV incidence is high among IDUs in Xinjiang, China. Baseline predictors of incidence and retention were minimal. The participant retention rate in this study is promising for the undertaking of future HIV intervention studies.

KW - China

KW - HIV

KW - IDUs

KW - Incidence

KW - Retention

KW - Xinjiang

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AN - SCOPUS:34347204435

SN - 1201-9712

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EP - 323

JO - International Journal of Infectious Diseases

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ER -

HIV incidence, retention rate, and baseline predictors of HIV incidence and retention in a prospective cohort study of injection drug users in Xinjiang, China

Abstract

Bibliographical note

Keywords

UN SDGs

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