HIV-1 and IL-1β regulate astrocytic CD38 through mitogen-activated protein kinases and nuclear factor-κB signaling mechanisms

Keyphrases

• Activated Astrocytes 13%
• Activity Assay 6%
• ADP-ribosyltransferase 6%
• Astrocyte Activation 13%
• Astrocytes 73%
• Astrocytic 100%
• Brain Tissue 6%
• Calcium Signaling 6%
• CD38 100%
• CD38 Expression 20%
• CD38 Gene 13%
• Chemokine (C-C motif) Ligand 2 (CCL2) 6%
• CXCL8 6%
• Dementia 6%
• Direct Participation 6%
• Dominant Negative 6%
• Dose Effect 6%
• Encephalitis 13%
• Gene Expression 20%
• Gene Expression Assay 6%
• HIV-associated Dementia 6%
• HIV-associated Neurocognitive Disorders 13%
• Human Astrocytes 6%
• Human Immunodeficiency Virus Type 1 (HIV-1) 100%
• Immunostaining 6%
• Induced Astrocytes 6%
• Infected Population 6%
• Inflammatory Chemokines 6%
• Inhibitor Factor 6%
• Interfering Peptides 6%
• Interleukin 6%
• Interleukin-1β 100%
• Mitogen-activated Protein Kinase 100%
• Mitogen-activated Protein Kinase Inhibitor 13%
• MRNA Expression 6%
• Neurocognitive Disorders 6%
• Nuclear factor-B 100%
• Proinflammatory Stimuli 6%
• Protein Expression 13%
• Quantitative PCR 6%
• Regulatory Mechanism 6%
• Response to Infection 6%
• SB203580 6%
• Severe Disease 6%
• Signaling Mechanism 100%
• SN50 13%
• SP600125 6%
• Transcription Factor 6%
• U0126 6%
• Viral Transfection 6%
• Virus 6%
• Western Blot Analysis 6%

Neuroscience

• Aciclovir 5%
• ADP Ribosyl Cyclase 5%
• Alternative Complement Pathway C3 C5 Convertase 100%
• Astrocyte 88%
• Calcium Signaling 5%
• CCL2 5%
• CD38 100%
• Cell Signaling 5%
• Chemokine 5%
• ELISA 5%
• Encephalitis 11%
• Gene Expression 22%
• HIV Associated Dementia 5%
• Human Immunodeficiency Virus 100%
• Immunohistochemistry 5%
• Interleukin 5%
• Interleukin 1 100%
• Mitogen-Activated Protein Kinase 100%
• Nuclear Factor 100%
• Protein Expression 11%
• Protein Kinase Inhibitor 11%
• Real-Time Polymerase Chain Reaction 5%
• Signaling Mechanism 100%
• Sn 50 11%
• Transcription Factors 5%
• Transfection 16%
• U0126 5%
• Viral Gene Delivery System 5%
• Western Blot 5%

Immunology and Microbiology

• Astrocyte 88%
• Brain Tissue 5%
• Calcium Signaling 5%
• CCL2 5%
• CD38 100%
• Chemokine 5%
• Complement Factor B 100%
• Cytokine 5%
• ELISA 5%
• Encephalitis 11%
• Gene Expression 22%
• Genetic Transfection 16%
• Human Immunodeficiency Virus 1 100%
• Immunostaining 5%
• Interleukin 5%
• Interleukin 1 100%
• Mitogen 100%
• Protein Expression 11%
• Real Time Polymerase Chain Reaction 5%
• Signal Transduction 5%
• Signaling Mechanism 100%
• Transcription Factors 5%
• Upregulation 5%
• Viral Gene Delivery System 5%
• Western Blot 5%