History of cardiac transplantation: Research, discoveries, and pioneers

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The first successful heart transplant could not have been possible without the vision, clinical skills, leadership, and persistence of dedicated physicians and researchers. Since then, these same qualities held by a broader group of clinicians have led to significant improvements over time. Examples of breakthroughs responsible for transplant success include vascular anastomosis, cardiopulmonary bypass, and the discovery of cyclosporine A. This chapter describes the many challenges, contributions, and innovations of cardiovascular experts such as Norman Shumway, MD, widely considered "the father of heart transplantation," and C. Walton Lillehei, MD, considered "the father of open heart surgery." Even Charles Lindbergh collaborated with Nobel Prize winner Alexis Carrel, MD, to develop the first working pump oxygenator used in organ perfusion.

Original languageEnglish (US)
Title of host publicationCongestive Heart Failure and Cardiac Transplantation
Subtitle of host publicationClinical, Pathology, Imaging and Molecular Profiles
PublisherSpringer International Publishing
Pages417-429
Number of pages13
ISBN (Electronic)9783319445779
ISBN (Print)9783319445755
DOIs
StatePublished - Jun 1 2017

Keywords

  • Cardiac transplantation
  • Cardiopulmonary bypass
  • Cross-circulation perfusion
  • Cyclosporine A
  • Dr. C. Walton Lillehei
  • Dr. Norman Shumway
  • Heart transplant history

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