Histoplasmosis may be common in East Africa but the diagnosis is rarely confirmed. We report 9 (0.9%) cases of probable histoplasmosis retrospectively identified among 970 febrile inpatients studied in northern Tanzania. Median (range) age was 31 (6, 44) years, 6 (67%) were female, 6 (67%) HIV-infected; 7 (78%) were clinically diagnosed with tuberculosis or bacterial pneumonia. Histoplasmosis is an important cause of febrile illness in Tanzania but is rarely considered in the differential diagnosis. Increased clinician awareness and availability of reliable diagnostic tests may improve patient outcomes.
|Original language||English (US)|
|Number of pages||4|
|Journal||Transactions of the Royal Society of Tropical Medicine and Hygiene|
|State||Published - Aug 2012|
Bibliographical noteFunding Information:
This research was supported by an International Studies on AIDS Associated Co-infections (ISAAC) award, a United States National Institutes of Health (NIH) funded program (U01 AI062563). Authors received support from NIH awards ISAAC (ABM, VPM, LJM, GDK, HOR, JAC); AIDS International Training and Research Program D43 PA-03-018 (ABM, VPM, HOR, JAC); the Duke Clinical Trials Unit and Clinical Research Sites U01 AI069484 (VPM, JAC), the Duke Center for AIDS Research P30 AI 64518 (L-YY, S-CC); the Center for HIV/AIDS Vaccine Immunology U01 AI067854 (JAC); and the Hubert-Yeargan Center for Global Health at Duke University (SML).