TY - JOUR
T1 - Histopathology of vascular anomalies
T2 - Update based on the revised 2014 ISSVA classification
AU - Miller, Daniel D.
AU - Gupta, Anita
PY - 2016/1/1
Y1 - 2016/1/1
N2 - Precise diagnosis of childhood vascular anomalies is challenging, and requires careful correlation of clinical findings, diagnostic imaging, histopathology and genetic analysis. Skin and soft tissue biopsies remain an important element in the complete evaluation of many vascular anomalies included in the revised 2014 International Society for the Study of Vascular Anomalies (ISSVA) classification. Here we present an overview of the light microscopic and immunohistochemical features of the entities in this updated classification scheme, with emphasis on newly-included diagnoses such as PTEN hamartoma of soft tissue.
AB - Precise diagnosis of childhood vascular anomalies is challenging, and requires careful correlation of clinical findings, diagnostic imaging, histopathology and genetic analysis. Skin and soft tissue biopsies remain an important element in the complete evaluation of many vascular anomalies included in the revised 2014 International Society for the Study of Vascular Anomalies (ISSVA) classification. Here we present an overview of the light microscopic and immunohistochemical features of the entities in this updated classification scheme, with emphasis on newly-included diagnoses such as PTEN hamartoma of soft tissue.
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UR - http://www.scopus.com/inward/citedby.url?scp=85020319479&partnerID=8YFLogxK
U2 - 10.12788/j.sder.2016.053
DO - 10.12788/j.sder.2016.053
M3 - Article
C2 - 27607322
AN - SCOPUS:85020319479
VL - 35
SP - 137
EP - 146
JO - Seminars in Cutaneous Medicine and Surgery
JF - Seminars in Cutaneous Medicine and Surgery
SN - 1085-5629
IS - 3
ER -