Objective: To report the ocular histopathologic features of a 55-year-old patient with incontinentia pigmenti retinopathy. Design: Observational case report. Participant: A 55-year-old patient with incontinentia pigmenti retinopathy. Methods: Examination of eyes by light microscopy and retinal trypsin digestion. Main Outcome Measures: Clinical and histopathological findings. Results: Histopathologic examination disclosed inner retinal ischemic atrophy, capillary beading, arteriolar-venous anastomoses, preretinal neovascularization, vasculopathy located at the junction of central vascular and peripheral avascular retina, retinal tears, and tractional retinoschisis. Conclusions: Patients with retinal manifestations of incontinentia pigmenti may progress to proliferative vitreoretinopathy or retinal detachment and should be observed closely over the course of their lifetime.
Bibliographical noteFunding Information:
Supported in part by Independent Order of Odd Fellows, Winston-Salem, North Carolina (WRG), and the Guerrieri Retinal Research Fund at the Wilmer Eye Institute (MFG).
Copyright 2008 Elsevier B.V., All rights reserved.