Highly efficient friedel-crafts alkylation of indoles and pyrrole catalyzed by mesoporous 3D aluminosilicate catalyst with electron-deficient olefins

The C3-selective Friedel-Crafts alkylation of indoles with electron-deficient olefins has been achieved using a mesoporous aluminosilicate catalyst with 3D cage-type porous structure to furnish the 3-alkylindole derivatives in excellent yields due to its high surface area, large pore volume and high acidity. Pyrrole also reacted efficiently under similar reaction conditions to give the corresponding 2-alkylated pyrrole derivatives in good yields.