Highly diastereoselective one-pot four-component coupling of p-TolSCl, 1-methoxycycloalkene, methyl vinyl ether and a carbon nucleophile leading to the synthesis of polyfunctional compounds

Margarita I. Lazareva; Yury K. Kryschenko; Ron Caple; Victor G Young; William A. Smit

doi:10.1070/mc1999v009n01abeh001044

Highly diastereoselective one-pot four-component coupling of p-TolSCl, 1-methoxycycloalkene, methyl vinyl ether and a carbon nucleophile leading to the synthesis of polyfunctional compounds

Margarita I. Lazareva
, Yury K. Kryschenko
, Ron Caple
, Victor G Young
, William A. Smit

Chemistry (Twin Cities)

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

An one-pot TiCl₄ initiated assemblage of polyfunctional compounds via a sequential coupling of p-TolSCl, 1-methoxycycloalkene, methyl vinyl ether and Sn-or Si-capped carbon nucleophile is shown to proceed with high diastereoselectivity at all newly created chiral centres.

Original language	English (US)
Pages (from-to)	24-25
Number of pages	2
Journal	Mendeleev Communications
Volume	9
Issue number	1
DOIs	https://doi.org/10.1070/mc1999v009n01abeh001044
State	Published - 1999

Bibliographical note

Funding Information:
This work was supported by the National Science Foundation (grant no. 8921358), the U.S. Civilian Research and Development Foundation (award no. RC2-141) and the Russian Foundation for Basic Research (grant no. 98-03-32970a).

Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.

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10.1070/mc1999v009n01abeh001044

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Highly diastereoselective one-pot four-component coupling of p-TolSCl, 1-methoxycycloalkene, methyl vinyl ether and a carbon nucleophile leading to the synthesis of polyfunctional compounds. / Lazareva, Margarita I.; Kryschenko, Yury K.; Caple, Ron et al.
In: Mendeleev Communications, Vol. 9, No. 1, 1999, p. 24-25.

Research output: Contribution to journal › Article › peer-review

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title = "Highly diastereoselective one-pot four-component coupling of p-TolSCl, 1-methoxycycloalkene, methyl vinyl ether and a carbon nucleophile leading to the synthesis of polyfunctional compounds",

abstract = "An one-pot TiCl4 initiated assemblage of polyfunctional compounds via a sequential coupling of p-TolSCl, 1-methoxycycloalkene, methyl vinyl ether and Sn-or Si-capped carbon nucleophile is shown to proceed with high diastereoselectivity at all newly created chiral centres.",

author = "Lazareva, \{Margarita I.\} and Kryschenko, \{Yury K.\} and Ron Caple and Young, \{Victor G\} and Smit, \{William A.\}",

note = "Funding Information: This work was supported by the National Science Foundation (grant no. 8921358), the U.S. Civilian Research and Development Foundation (award no. RC2-141) and the Russian Foundation for Basic Research (grant no. 98-03-32970a). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.",

year = "1999",

doi = "10.1070/mc1999v009n01abeh001044",

language = "English (US)",

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AU - Lazareva, Margarita I.

AU - Kryschenko, Yury K.

AU - Caple, Ron

AU - Young, Victor G

AU - Smit, William A.

N1 - Funding Information: This work was supported by the National Science Foundation (grant no. 8921358), the U.S. Civilian Research and Development Foundation (award no. RC2-141) and the Russian Foundation for Basic Research (grant no. 98-03-32970a). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.

PY - 1999

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N2 - An one-pot TiCl4 initiated assemblage of polyfunctional compounds via a sequential coupling of p-TolSCl, 1-methoxycycloalkene, methyl vinyl ether and Sn-or Si-capped carbon nucleophile is shown to proceed with high diastereoselectivity at all newly created chiral centres.

AB - An one-pot TiCl4 initiated assemblage of polyfunctional compounds via a sequential coupling of p-TolSCl, 1-methoxycycloalkene, methyl vinyl ether and Sn-or Si-capped carbon nucleophile is shown to proceed with high diastereoselectivity at all newly created chiral centres.

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UR - https://www.scopus.com/pages/publications/0040626229#tab=citedBy

U2 - 10.1070/mc1999v009n01abeh001044

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JO - Mendeleev Communications

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IS - 1

ER -

Highly diastereoselective one-pot four-component coupling of p-TolSCl, 1-methoxycycloalkene, methyl vinyl ether and a carbon nucleophile leading to the synthesis of polyfunctional compounds

Abstract

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