TY - JOUR
T1 - High-valent nonheme iron-oxo complexes
T2 - Synthesis, structure, and spectroscopy
AU - McDonald, Aidan R.
AU - Que, Lawrence
PY - 2013/1/5
Y1 - 2013/1/5
N2 - High-valent iron-oxo intermediates have often been implicated, and in some cases identified, as the active oxidant in oxygen activating nonheme iron enzymes. Recent synthetic efforts have yielded pivotal insights into the generation of oxoiron(IV and V) complexes, and allowed thorough investigation of their spectroscopic, structural, and electronic properties. Furthermore, insight into the mechanisms by which nonheme iron sites activate dioxygen to yield high valent iron-oxo intermediates has been obtained. This review covers the great successes in iron-oxo chemistry over the past decade, detailing various efforts to obtain iron-oxo complexes in high yield, and to delve into their diverse structural and spectroscopic properties.
AB - High-valent iron-oxo intermediates have often been implicated, and in some cases identified, as the active oxidant in oxygen activating nonheme iron enzymes. Recent synthetic efforts have yielded pivotal insights into the generation of oxoiron(IV and V) complexes, and allowed thorough investigation of their spectroscopic, structural, and electronic properties. Furthermore, insight into the mechanisms by which nonheme iron sites activate dioxygen to yield high valent iron-oxo intermediates has been obtained. This review covers the great successes in iron-oxo chemistry over the past decade, detailing various efforts to obtain iron-oxo complexes in high yield, and to delve into their diverse structural and spectroscopic properties.
KW - Bioinorganic chemistry
KW - Dioxygen activation
KW - Iron-oxo complexes
KW - Nonheme iron
UR - http://www.scopus.com/inward/record.url?scp=84870393197&partnerID=8YFLogxK
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U2 - 10.1016/j.ccr.2012.08.002
DO - 10.1016/j.ccr.2012.08.002
M3 - Review article
AN - SCOPUS:84870393197
VL - 257
SP - 414
EP - 428
JO - Coordination Chemistry Reviews
JF - Coordination Chemistry Reviews
SN - 0010-8545
IS - 2
ER -