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High-dose-rate intraoperative radiation therapy: The nuts and bolts of starting a program

  • Shalini Moningi
  • , Elwood P. Armour
  • , Stephanie A. Terezakis
  • , Jonathan E. Efron
  • , Susan L. Gearhart
  • , Trinity J. Bivalacqua
  • , Rachit Kumar
  • , Yi Le
  • , Sook Kien Ng
  • , Christopher L. Wolfgang
  • , Richard C. Zellars
  • , Susannah G. Ellsworth
  • , Nita Ahuja
  • , Joseph M. Herman

Research output: Contribution to journalReview articlepeer-review

Abstract

High-dose-rate intraoperative radiation therapy (HDR-IORT) has historically provided effective local control (LC) for patients with unresectable and recurrent tumors. However, IORT is limited to only a few specialized institutions and it can be difficult to initiate an HDR-IORT program. Herein, we provide a brief overview on how to initiate and implement an HDR-IORT program for a selected group of patients with gastrointestinal and pelvic solid tumors using a multidisciplinary approach. Proper administration of HDR-IORT requires institutional support and a joint effort among physics staff, oncologists, surgeons, anesthesiologists, and nurses. In order to determine the true efficacy of IORT for various malignancies, collaboration among institutions with established IORT programs is needed.

Original languageEnglish (US)
Pages (from-to)99-105
Number of pages7
JournalJournal of Contemporary Brachytherapy
Volume6
Issue number1
DOIs
StatePublished - 2014
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • High-dose-rate brachytherapy
  • Intraoperative radiation therapy
  • Recurrent tumors
  • Sarcoma

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