TY - JOUR
T1 - High-dose-rate intraoperative radiation therapy
T2 - The nuts and bolts of starting a program
AU - Moningi, Shalini
AU - Armour, Elwood P.
AU - Terezakis, Stephanie A.
AU - Efron, Jonathan E.
AU - Gearhart, Susan L.
AU - Bivalacqua, Trinity J.
AU - Kumar, Rachit
AU - Le, Yi
AU - Ng, Sook Kien
AU - Wolfgang, Christopher L.
AU - Zellars, Richard C.
AU - Ellsworth, Susannah G.
AU - Ahuja, Nita
AU - Herman, Joseph M.
PY - 2014
Y1 - 2014
N2 - High-dose-rate intraoperative radiation therapy (HDR-IORT) has historically provided effective local control (LC) for patients with unresectable and recurrent tumors. However, IORT is limited to only a few specialized institutions and it can be difficult to initiate an HDR-IORT program. Herein, we provide a brief overview on how to initiate and implement an HDR-IORT program for a selected group of patients with gastrointestinal and pelvic solid tumors using a multidisciplinary approach. Proper administration of HDR-IORT requires institutional support and a joint effort among physics staff, oncologists, surgeons, anesthesiologists, and nurses. In order to determine the true efficacy of IORT for various malignancies, collaboration among institutions with established IORT programs is needed.
AB - High-dose-rate intraoperative radiation therapy (HDR-IORT) has historically provided effective local control (LC) for patients with unresectable and recurrent tumors. However, IORT is limited to only a few specialized institutions and it can be difficult to initiate an HDR-IORT program. Herein, we provide a brief overview on how to initiate and implement an HDR-IORT program for a selected group of patients with gastrointestinal and pelvic solid tumors using a multidisciplinary approach. Proper administration of HDR-IORT requires institutional support and a joint effort among physics staff, oncologists, surgeons, anesthesiologists, and nurses. In order to determine the true efficacy of IORT for various malignancies, collaboration among institutions with established IORT programs is needed.
KW - High-dose-rate brachytherapy
KW - Intraoperative radiation therapy
KW - Recurrent tumors
KW - Sarcoma
UR - http://www.scopus.com/inward/record.url?scp=84899551989&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84899551989&partnerID=8YFLogxK
U2 - 10.5114/jcb.2014.42027
DO - 10.5114/jcb.2014.42027
M3 - Review article
AN - SCOPUS:84899551989
SN - 1689-832X
VL - 6
SP - 99
EP - 105
JO - Journal of Contemporary Brachytherapy
JF - Journal of Contemporary Brachytherapy
IS - 1
ER -