HIF hits Wnt in the stem cell niche

Dan S. Kaufman

doi:10.1038/ncb1010-926

HIF hits Wnt in the stem cell niche

Dan S. Kaufman

Research output: Contribution to journal › Short survey › peer-review

27 Scopus citations

Abstract

Distinct stem-cell populations are known to reside in hypoxic niches during development and postnatal life. Hypoxia-inducible transcription factors (HIFs) directly regulate the Wnt/β-catenin pathway to ensure the maintenance of both adult and embryonic stem cells.

Original language	English (US)
Pages (from-to)	926-927
Number of pages	2
Journal	Nature Cell Biology
Volume	12
Issue number	10
DOIs	https://doi.org/10.1038/ncb1010-926
State	Published - Oct 2010
Externally published	Yes

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10.1038/ncb1010-926

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title = "HIF hits Wnt in the stem cell niche",

abstract = "Distinct stem-cell populations are known to reside in hypoxic niches during development and postnatal life. Hypoxia-inducible transcription factors (HIFs) directly regulate the Wnt/β-catenin pathway to ensure the maintenance of both adult and embryonic stem cells.",

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AB - Distinct stem-cell populations are known to reside in hypoxic niches during development and postnatal life. Hypoxia-inducible transcription factors (HIFs) directly regulate the Wnt/β-catenin pathway to ensure the maintenance of both adult and embryonic stem cells.

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M3 - Short survey

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JO - Nature Cell Biology

JF - Nature Cell Biology

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ER -

HIF hits Wnt in the stem cell niche

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