HIF hits Wnt in the stem cell niche

Dan S. Kaufman

Research output: Contribution to journalShort surveypeer-review

27 Scopus citations


Distinct stem-cell populations are known to reside in hypoxic niches during development and postnatal life. Hypoxia-inducible transcription factors (HIFs) directly regulate the Wnt/β-catenin pathway to ensure the maintenance of both adult and embryonic stem cells.

Original languageEnglish (US)
Pages (from-to)926-927
Number of pages2
JournalNature Cell Biology
Issue number10
StatePublished - Oct 2010
Externally publishedYes


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