Hidden Complexity in Routine Adult and Pediatric Arrhythmias Interpretation: The Future of Precision Electrocardiology

Fabio M. Leonelli; Roberto De Ponti; Fabrizio Drago; Anwar Baban; Daniel Cortez; Massimo Griselli; Giuseppe Bagliani

doi:10.1016/j.ccep.2019.03.001

Hidden Complexity in Routine Adult and Pediatric Arrhythmias Interpretation: The Future of Precision Electrocardiology

Fabio M. Leonelli, Roberto De Ponti, Fabrizio Drago, Anwar Baban, Daniel Cortez, Massimo Griselli, Giuseppe Bagliani

Research output: Contribution to journal › Review article › peer-review

Abstract

Classic ECG interpretation is based on identification of waveforms and deductive analysis of the electrical events the waveforms represent. The more in depth the understanding of electrophysiologic cellular interactions, the more precise the interpretation of ECG tracing. Surface ECG has limitations; yet, it is accurate in representing myocytes’ pathologic behaviors. Recent advances have improved understanding of arrhythmias by reconstructing their mechanisms of induction and maintenance and exploring cellular channel dysfunction. Translating this knowledge to ECG analysis will create the link that allows ECG interpretation to reach the level of precision electrocardiology. This article presents cases illustrating new techniques for electrophysiologists.

Original language	English (US)
Pages (from-to)	391-404
Number of pages	14
Journal	Cardiac Electrophysiology Clinics
Volume	11
Issue number	2
DOIs	https://doi.org/10.1016/j.ccep.2019.03.001
State	Published - Jun 2019

Bibliographical note

Publisher Copyright:
© 2019 Elsevier Inc.

Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.

Keywords

Arrhythmias
Channelopathies
ECG
Genetic testing
Precision electro cardiology

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10.1016/j.ccep.2019.03.001

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title = "Hidden Complexity in Routine Adult and Pediatric Arrhythmias Interpretation: The Future of Precision Electrocardiology",

abstract = "Classic ECG interpretation is based on identification of waveforms and deductive analysis of the electrical events the waveforms represent. The more in depth the understanding of electrophysiologic cellular interactions, the more precise the interpretation of ECG tracing. Surface ECG has limitations; yet, it is accurate in representing myocytes{\textquoteright} pathologic behaviors. Recent advances have improved understanding of arrhythmias by reconstructing their mechanisms of induction and maintenance and exploring cellular channel dysfunction. Translating this knowledge to ECG analysis will create the link that allows ECG interpretation to reach the level of precision electrocardiology. This article presents cases illustrating new techniques for electrophysiologists.",

keywords = "Arrhythmias, Channelopathies, ECG, Genetic testing, Precision electro cardiology",

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year = "2019",

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doi = "10.1016/j.ccep.2019.03.001",

language = "English (US)",

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AU - Leonelli, Fabio M.

AU - De Ponti, Roberto

AU - Drago, Fabrizio

AU - Baban, Anwar

AU - Cortez, Daniel

AU - Griselli, Massimo

AU - Bagliani, Giuseppe

PY - 2019/6

Y1 - 2019/6

N2 - Classic ECG interpretation is based on identification of waveforms and deductive analysis of the electrical events the waveforms represent. The more in depth the understanding of electrophysiologic cellular interactions, the more precise the interpretation of ECG tracing. Surface ECG has limitations; yet, it is accurate in representing myocytes’ pathologic behaviors. Recent advances have improved understanding of arrhythmias by reconstructing their mechanisms of induction and maintenance and exploring cellular channel dysfunction. Translating this knowledge to ECG analysis will create the link that allows ECG interpretation to reach the level of precision electrocardiology. This article presents cases illustrating new techniques for electrophysiologists.

AB - Classic ECG interpretation is based on identification of waveforms and deductive analysis of the electrical events the waveforms represent. The more in depth the understanding of electrophysiologic cellular interactions, the more precise the interpretation of ECG tracing. Surface ECG has limitations; yet, it is accurate in representing myocytes’ pathologic behaviors. Recent advances have improved understanding of arrhythmias by reconstructing their mechanisms of induction and maintenance and exploring cellular channel dysfunction. Translating this knowledge to ECG analysis will create the link that allows ECG interpretation to reach the level of precision electrocardiology. This article presents cases illustrating new techniques for electrophysiologists.

KW - Arrhythmias

KW - Channelopathies

KW - ECG

KW - Genetic testing

KW - Precision electro cardiology

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Hidden Complexity in Routine Adult and Pediatric Arrhythmias Interpretation: The Future of Precision Electrocardiology

Abstract

Bibliographical note

Keywords

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