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Heteronuclear NMR and crystallographic studies of wild-type and H187Q Escherichia coli uracil DNA glycosylase: Electrophilic catalysis of uracil expulsion by a neutral histidine 187

  • Alexander C. Drohat
  • , Gaoyi Xiao
  • , Maria Tordova
  • , Jaya Jagadeesh
  • , Krzysztof W. Pankiewicz
  • , Kyoichi A. Watanabe
  • , Gary L. Gilliland
  • , James T. Stivers

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Biochemistry, Genetics and Molecular Biology