Selective carboxylic acid decarboxylation was elaborated. Generation of acyltrifluoroacetyl peroxides from carboxylic peracids and trifluoroacetyl anhydride (Method A), as well as from trifluoroperacetic acid and acyltrifluoroacetyl anhydride (Method B), leads to simultaneous peroxide decomposition into the corresponding alkyltrifluoroacetates. DFT computations, as well as experimental data, support an acid-catalyzed heterolytic mechanism for acyltrifluoroacetyl peroxide decomposition.
|Original language||English (US)|
|Number of pages||5|
|State||Published - Nov 25 2002|
Bibliographical noteFunding Information:
A portion of this work was supported by the International Soros Foundation (Reg # иCC000). We are also grateful to the US Civilian Research and Development Foundation (CRDF) for Travel Grant (TGP-438 for A.A.F.) and to Dr. Nico J. R. van Eikema Hommes (University Erlangen-Nürnberg) for the use of the ‘Molecule’ program.