Abstract
Paget disease of the bone is a common skeletal disorder. Recently, a gene for Paget disease was localized to 18q with subsequent evidence for linkage heterogeneity. We report the identification and clinical characterization of a large pedigree of Paget disease and demonstrate that the Paget disease gene in this pedigree is not linked to the region on 18q, thus confirming linkage heterogeneity. (C) 2000 Wiley-Liss, Inc.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 303-307 |
| Number of pages | 5 |
| Journal | American Journal of Medical Genetics |
| Volume | 92 |
| Issue number | 5 |
| DOIs | |
| State | Published - Jun 19 2000 |
Keywords
- Heterogeneity
- Paget disease