Hereditary dysautonomias: Current knowledge and collaborations for the future

Math P. Cuajungco, Yukio Ando, Felicia B. Axelrod, Italo Biaggioni, David S. Goldstein, Alan E. Guttmacher, Katrina Gwinn-Hardy, Maureen K. Hahn, Max J. Hilz, Giris Jacob, Jordan Jens, William R. Kennedy, Stephen B. Liggett, Daniel T. O'Connor, Sonia R. Peltzer, David Robertson, Berish Y. Rubin, Quandra Scudder, Linda J. Smith, Gail E. SonensheinJesper Q. Svejstrup, Yang Xu, Susan A. Slaugenhaupt

Research output: Contribution to journalArticlepeer-review

Abstract

The hereditary dysautonomias (H-Dys) are a large group of disorders that affect the autonomic nervous system. Research in the field of H-Dys is very challenging, because the disorders involve interdisciplinary, integrative, and "mind-body" connections. Recently, medical scientists, NIH/ NINDS representatives, and several patient support groups gathered for the first time in order to discuss recent findings and future directions in the H-Dys field. The H-Dys workshop was instrumental in promoting interactions between basic science and clinical investigators. It also allowed attendees to have an opportunity to meet each other, understand the similarities between the various forms of dysautonomia, and experience the unique perspective offered by patients and their families. Future advances in H-Dys research will depend on a novel multi-system approach by investigators from different medical disciplines, and it is hoped that towards a common goal, novel "bench-to-bedside" therapeutics will be developed to improve the lives of, or even cure, patients suffering from dysautonomic syndromes.

Original languageEnglish (US)
Pages (from-to)180-195
Number of pages16
JournalClinical Autonomic Research
Volume13
Issue number3
DOIs
StatePublished - Jun 2003

Keywords

  • Amyloidosis
  • Autonomic nervous system
  • Catecholamine
  • Neuropathy

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