Hereditary dysautonomias: Current knowledge and collaborations for the future

Math P. Cuajungco; Yukio Ando; Felicia B. Axelrod; Italo Biaggioni; David S. Goldstein; Alan E. Guttmacher; Katrina Gwinn-Hardy; Maureen K. Hahn; Max J. Hilz; Giris Jacob; Jordan Jens; William R. Kennedy; Stephen B. Liggett; Daniel T. O'Connor; Sonia R. Peltzer; David Robertson; Berish Y. Rubin; Quandra Scudder; Linda J. Smith; Gail E. Sonenshein; Jesper Q. Svejstrup; Yang Xu; Susan A. Slaugenhaupt

doi:10.1007/s10286-003-0098-2

Hereditary dysautonomias: Current knowledge and collaborations for the future

Math P. Cuajungco, Yukio Ando, Felicia B. Axelrod, Italo Biaggioni, David S. Goldstein, Alan E. Guttmacher, Katrina Gwinn-Hardy, Maureen K. Hahn, Max J. Hilz, Giris Jacob, Jordan Jens, William R. Kennedy, Stephen B. Liggett, Daniel T. O'Connor, Sonia R. Peltzer, David Robertson, Berish Y. Rubin, Quandra Scudder, Linda J. Smith, Gail E. SonensheinJesper Q. Svejstrup, Yang Xu, Susan A. Slaugenhaupt

Neurology

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The hereditary dysautonomias (H-Dys) are a large group of disorders that affect the autonomic nervous system. Research in the field of H-Dys is very challenging, because the disorders involve interdisciplinary, integrative, and "mind-body" connections. Recently, medical scientists, NIH/ NINDS representatives, and several patient support groups gathered for the first time in order to discuss recent findings and future directions in the H-Dys field. The H-Dys workshop was instrumental in promoting interactions between basic science and clinical investigators. It also allowed attendees to have an opportunity to meet each other, understand the similarities between the various forms of dysautonomia, and experience the unique perspective offered by patients and their families. Future advances in H-Dys research will depend on a novel multi-system approach by investigators from different medical disciplines, and it is hoped that towards a common goal, novel "bench-to-bedside" therapeutics will be developed to improve the lives of, or even cure, patients suffering from dysautonomic syndromes.

Original language	English (US)
Pages (from-to)	180-195
Number of pages	16
Journal	Clinical Autonomic Research
Volume	13
Issue number	3
DOIs	https://doi.org/10.1007/s10286-003-0098-2
State	Published - Jun 2003

Bibliographical note

Funding Information:
■ Acknowledgments We thank the org anizers of the first workshop in dysautonomia for making it a success. Funding for the H-Dys Workshop was provided by the NINDS and the ORD, NIH. We thank Ms. Debra Kulik and Ms. Lee May for their help. We are also g rateful to the Dysautonomia Foundation, Inc., the Familial Dysautonomia Hope Foundation, and the National Dysautonomia Research Foundation for their continued financial support in all areas of dysautonomia research.

Keywords

Amyloidosis
Autonomic nervous system
Catecholamine
Neuropathy

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10.1007/s10286-003-0098-2

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Cuajungco, M. P., Ando, Y., Axelrod, F. B., Biaggioni, I., Goldstein, D. S., Guttmacher, A. E., Gwinn-Hardy, K., Hahn, M. K., Hilz, M. J., Jacob, G., Jens, J., Kennedy, W. R., Liggett, S. B., O'Connor, D. T., Peltzer, S. R., Robertson, D., Rubin, B. Y., Scudder, Q., Smith, L. J., ... Slaugenhaupt, S. A. (2003). Hereditary dysautonomias: Current knowledge and collaborations for the future. Clinical Autonomic Research, 13(3), 180-195. https://doi.org/10.1007/s10286-003-0098-2

Cuajungco, MP, Ando, Y, Axelrod, FB, Biaggioni, I, Goldstein, DS, Guttmacher, AE, Gwinn-Hardy, K, Hahn, MK, Hilz, MJ, Jacob, G, Jens, J, Kennedy, WR, Liggett, SB, O'Connor, DT, Peltzer, SR, Robertson, D, Rubin, BY, Scudder, Q, Smith, LJ, Sonenshein, GE, Svejstrup, JQ, Xu, Y & Slaugenhaupt, SA 2003, 'Hereditary dysautonomias: Current knowledge and collaborations for the future', Clinical Autonomic Research, vol. 13, no. 3, pp. 180-195. https://doi.org/10.1007/s10286-003-0098-2

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title = "Hereditary dysautonomias: Current knowledge and collaborations for the future",

abstract = "The hereditary dysautonomias (H-Dys) are a large group of disorders that affect the autonomic nervous system. Research in the field of H-Dys is very challenging, because the disorders involve interdisciplinary, integrative, and {"}mind-body{"} connections. Recently, medical scientists, NIH/ NINDS representatives, and several patient support groups gathered for the first time in order to discuss recent findings and future directions in the H-Dys field. The H-Dys workshop was instrumental in promoting interactions between basic science and clinical investigators. It also allowed attendees to have an opportunity to meet each other, understand the similarities between the various forms of dysautonomia, and experience the unique perspective offered by patients and their families. Future advances in H-Dys research will depend on a novel multi-system approach by investigators from different medical disciplines, and it is hoped that towards a common goal, novel {"}bench-to-bedside{"} therapeutics will be developed to improve the lives of, or even cure, patients suffering from dysautonomic syndromes.",

keywords = "Amyloidosis, Autonomic nervous system, Catecholamine, Neuropathy",

author = "Cuajungco, {Math P.} and Yukio Ando and Axelrod, {Felicia B.} and Italo Biaggioni and Goldstein, {David S.} and Guttmacher, {Alan E.} and Katrina Gwinn-Hardy and Hahn, {Maureen K.} and Hilz, {Max J.} and Giris Jacob and Jordan Jens and Kennedy, {William R.} and Liggett, {Stephen B.} and O'Connor, {Daniel T.} and Peltzer, {Sonia R.} and David Robertson and Rubin, {Berish Y.} and Quandra Scudder and Smith, {Linda J.} and Sonenshein, {Gail E.} and Svejstrup, {Jesper Q.} and Yang Xu and Slaugenhaupt, {Susan A.}",

note = "Funding Information: ■ Acknowledgments We thank the org anizers of the first workshop in dysautonomia for making it a success. Funding for the H-Dys Workshop was provided by the NINDS and the ORD, NIH. We thank Ms. Debra Kulik and Ms. Lee May for their help. We are also g rateful to the Dysautonomia Foundation, Inc., the Familial Dysautonomia Hope Foundation, and the National Dysautonomia Research Foundation for their continued financial support in all areas of dysautonomia research.",

year = "2003",

month = jun,

doi = "10.1007/s10286-003-0098-2",

language = "English (US)",

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AU - Ando, Yukio

AU - Axelrod, Felicia B.

AU - Biaggioni, Italo

AU - Goldstein, David S.

AU - Guttmacher, Alan E.

AU - Gwinn-Hardy, Katrina

AU - Hahn, Maureen K.

AU - Hilz, Max J.

AU - Jacob, Giris

AU - Jens, Jordan

AU - Kennedy, William R.

AU - Liggett, Stephen B.

AU - O'Connor, Daniel T.

AU - Peltzer, Sonia R.

AU - Robertson, David

AU - Rubin, Berish Y.

AU - Scudder, Quandra

AU - Smith, Linda J.

AU - Sonenshein, Gail E.

AU - Svejstrup, Jesper Q.

AU - Xu, Yang

AU - Slaugenhaupt, Susan A.

N1 - Funding Information: ■ Acknowledgments We thank the org anizers of the first workshop in dysautonomia for making it a success. Funding for the H-Dys Workshop was provided by the NINDS and the ORD, NIH. We thank Ms. Debra Kulik and Ms. Lee May for their help. We are also g rateful to the Dysautonomia Foundation, Inc., the Familial Dysautonomia Hope Foundation, and the National Dysautonomia Research Foundation for their continued financial support in all areas of dysautonomia research.

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Hereditary dysautonomias: Current knowledge and collaborations for the future

Abstract

Bibliographical note

Keywords

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