TY - JOUR
T1 - Hereditary cancer syndromes of the skin
AU - Somoano, Brian
AU - Niendorf, Kristin Baker
AU - Tsao, Hensin
PY - 2005
Y1 - 2005
N2 - Hereditary cancer syndromes are a group of disorders characterized by a genetic susceptibility to the development of malignant tumors. Multiple cancers in the family or an abnormally early onset for the given cancer may suggest an underlying inherited predisposition. Awareness of their associated dermatologic manifestations can facilitate early detection of risk for neoplasms. This article provides an update on the clinical features, diagnostic criteria, and the use of genetic analysis in the detection of causative mutations of those hereditary cancer syndromes with cutaneous manifestations.
AB - Hereditary cancer syndromes are a group of disorders characterized by a genetic susceptibility to the development of malignant tumors. Multiple cancers in the family or an abnormally early onset for the given cancer may suggest an underlying inherited predisposition. Awareness of their associated dermatologic manifestations can facilitate early detection of risk for neoplasms. This article provides an update on the clinical features, diagnostic criteria, and the use of genetic analysis in the detection of causative mutations of those hereditary cancer syndromes with cutaneous manifestations.
UR - http://www.scopus.com/inward/record.url?scp=13544277362&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=13544277362&partnerID=8YFLogxK
U2 - 10.1016/j.clindermatol.2004.09.012
DO - 10.1016/j.clindermatol.2004.09.012
M3 - Review article
C2 - 15708293
AN - SCOPUS:13544277362
SN - 0738-081X
VL - 23
SP - 85
EP - 106
JO - Clinics in Dermatology
JF - Clinics in Dermatology
IS - 1
ER -
