Hereditary cancer syndromes of the skin

Brian Somoano; Kristin B Niendorf; Hensin Tsao

doi:10.1016/j.clindermatol.2004.09.012

Hereditary cancer syndromes of the skin

Brian Somoano, Kristin B Niendorf, Hensin Tsao

Surgery

Research output: Contribution to journal › Review article › peer-review

14 Scopus citations

Abstract

Hereditary cancer syndromes are a group of disorders characterized by a genetic susceptibility to the development of malignant tumors. Multiple cancers in the family or an abnormally early onset for the given cancer may suggest an underlying inherited predisposition. Awareness of their associated dermatologic manifestations can facilitate early detection of risk for neoplasms. This article provides an update on the clinical features, diagnostic criteria, and the use of genetic analysis in the detection of causative mutations of those hereditary cancer syndromes with cutaneous manifestations.

Original language	English (US)
Pages (from-to)	85-106
Number of pages	22
Journal	Clinics in Dermatology
Volume	23
Issue number	1
DOIs	https://doi.org/10.1016/j.clindermatol.2004.09.012
State	Published - Jan 1 2005

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abstract = "Hereditary cancer syndromes are a group of disorders characterized by a genetic susceptibility to the development of malignant tumors. Multiple cancers in the family or an abnormally early onset for the given cancer may suggest an underlying inherited predisposition. Awareness of their associated dermatologic manifestations can facilitate early detection of risk for neoplasms. This article provides an update on the clinical features, diagnostic criteria, and the use of genetic analysis in the detection of causative mutations of those hereditary cancer syndromes with cutaneous manifestations.",

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N2 - Hereditary cancer syndromes are a group of disorders characterized by a genetic susceptibility to the development of malignant tumors. Multiple cancers in the family or an abnormally early onset for the given cancer may suggest an underlying inherited predisposition. Awareness of their associated dermatologic manifestations can facilitate early detection of risk for neoplasms. This article provides an update on the clinical features, diagnostic criteria, and the use of genetic analysis in the detection of causative mutations of those hereditary cancer syndromes with cutaneous manifestations.

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