Hepatotoxicity and cholestasis in rats induced by the sesquiterpene, 9-oxo-10,11-dehydroageraphorone, isolated from Eupatorium adenophorum

Keyphrases

• Cholestasis 100%
• Hepatotoxicity 100%
• Eupatorium Adenophorum 100%
• Sesquiterpenes 100%
• OXA-10 100%
• 11-dehydroageraphorone 100%
• Glutamic Pyruvic Transaminase 50%
• Liver 25%
• Oral Administration 25%
• Jaundice 25%
• Pathological Lesions 25%
• Alkaline Phosphatase 25%
• Lactate Dehydrogenase 25%
• Glutamyl Transpeptidase 25%
• Glutamate Dehydrogenase 25%
• Biochemical Profile 25%
• Marker Enzymes 25%
• Bile Duct 25%
• Induced Hepatotoxicity 25%
• Bilirubin 25%
• 5′-nucleotidase 25%
• Hepatotoxicants 25%
• Degenerative Changes 25%
• Hepatocellular Necrosis 25%
• Lining Epithelium 25%
• Liver Profile 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Hepatotoxicity 100%
• Eupatorium 100%
• Cholestasis 100%
• Sesquiterpene 100%
• Gamma Glutamyltransferase 33%
• Aspartate Aminotransferase 33%
• Alanine Aminotransferase 33%
• Liver Necrosis 33%
• Bilirubin 33%
• 5' Nucleotidase 33%
• Alkaline Phosphatase 33%
• Glutamate Dehydrogenase 33%
• Lactate Dehydrogenase 33%
• Jaundice 33%