Hepatocellular carcinoma, a unique tumor with a lack of biomarkers

Jose D. Debes, Enrique Carrera, Angelo Z. Mattos, Jhon E. Prieto, Andre Boonstra

Research output: Contribution to journalComment/debatepeer-review

12 Scopus citations


Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death worldwide. Interestingly, the great majority of individuals affected by the tumor have underlying liver disease, therefore narrowing the population to be screened. Still, however, there is a clear lack of blood biomarkers, and surveillance in those at risk is performed by frequent imaging of the liver. A variety of multinational collaborations are currently invested in finding biomarkers for HCC based on liver-produced proteins. A new approach with assessment of peripheral proteins might be necessary for the successful early detection of this malignancy.

Original languageEnglish (US)
Pages (from-to)786-787
Number of pages2
JournalAnnals of Hepatology
Issue number6
StatePublished - Nov 1 2019

Bibliographical note

Publisher Copyright:
© 2019 Fundación Clínica Médica Sur, A.C.


  • Biomarkers
  • Blood
  • HCC


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