Henoch-Schonlein purpura and pulmonary hemorrhage: A report and literature review

Kalyani R. Vats, Abhay Vats, Youngki Kim, David Dassenko, Alan R Sinaiko

Research output: Contribution to journalArticlepeer-review

49 Scopus citations

Abstract

Pulmonary hemorrhage, a rare complication of Henoch-Schonlein purpura (HSP) reported primarily in adults and adolescents, is associated with significant mortality. Although it has been suggested that pulmonary hemorrhage also occurs in children with HSP, the few cases reported lack a clear differentiation from pauci-immune vasculitis. We report a prepubertal child with HSP, pulmonary hemorrhage, and immunofluorescence-documented IgA deposits on renal biopsy. Aggressive supportive management and steroid therapy led to successful recovery. A review of the current literature is presented. Because other conditions clinically mimic HSP, appropriate serological studies and a kidney biopsy to confirm the diagnosis should be performed in severely affected patients with renal disease.

Original languageEnglish (US)
Pages (from-to)530-534
Number of pages5
JournalPediatric Nephrology
Volume13
Issue number6
DOIs
StatePublished - Aug 1 1999

Keywords

  • Henoch-Schonlein purpura
  • IgA
  • Pulmonary hemorrhage

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