Henoch-Schönlein Vasculitis as a Manifestation of IgA-Associated Disease in Cirrhosis

Manju Aggarwal, Connie Manske, Peter J Lynch, Mark S Paller

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

Cirrhosis has been associated with a variety of glomerular lesions that generally include deposits of IgA in the mesangium. However, loss of renal function secondary to IgA deposition in cirrhotics is infrequent. An unusual patient who developed rapidly progressive glomerulonephritis followed by leukocytoclastic vasculitis with IgA deposition on skin biopsy is presented. We postulate that this is an example of Henoch-SchOnlein purpura occurring secondary to altered IgA processing in cirrhosis.

Original languageEnglish (US)
Pages (from-to)400-402
Number of pages3
JournalAmerican Journal of Kidney Diseases
Volume20
Issue number4
DOIs
StatePublished - Jan 1 1992

Keywords

  • Henoch-Schönlein vasculitis
  • IgA nephropathy
  • cirrhosis
  • glomerulonephritis
  • leukocytoclastic vasculitis

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