Hemodynamics of acute myocardial infarction comparison of 'uncomplicated' and mild left ventricular failure

Thirty five patients were studied hemodynamically (including measurement of pulmonary artery, PA, pressure and cardiac output, CO) within 72 hr of the onset of acute myocardial infarction (AMI). Subjects selected did not have the more serious complications of infarction, namely, prominent left ventricular failure (LVF), shock or persistent arrhythmia. Twenty two patients were defined as 'uncomplicated' and 13 as mild LVF on the basis of an S-3 gallop and persistent posttussive rales. Hemodynamic data demonstrated considerable overlap between the two groups. The PA diastolic pressure and heart rate were significantly higher in the group with signs of mild LVF. Other measurements, including CO, heart rate, vascular resistance and stroke work index, were not significantly different. These data emphasize that no simple correlation exists between clinical signs and hemodynamic impairment in AMI. Also, patients as described in this report have a good immediate prognosis, regardless of findings, as none died during the hospitalization.