Hemodialysis in an infant with propoxyphene intoxication

S. Michael Mauer, Charles L. Paxson, Barry Von Hartizsch, Theodore J. Buselmeier, Carl M. Kielistrand

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

A 10-month-old infant was treated with intensive supportive care and hem odialysisfor severe propoxyphene intoxication. Dialysis clearance studies demonstrated that propoxyphene was removed from the serum at approximately 50% of the rate of blood urea nitrogen removal. Possibly because of tissue binding of the drug, the absolute quantity of propoxyphene removed by dialysis was small. The child survived the acute episode of intoxication but died of pulmonary complications several days later. The role of dialysis in propoxyphene intoxication remains to be established.

Original languageEnglish (US)
Pages (from-to)88-92
Number of pages5
JournalClinical pharmacology and therapeutics
Volume17
Issue number1
DOIs
StatePublished - Jan 1975

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