Hemodialysis catheter placement and recirculation in treatment of hyperammonemia

Abhay Vats, Clifford Kashtan, Mendel Tuchman, Michael Mauer

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

A 2-year-old girl with carbamoyl phosphate synthetase deficiency underwent emergency hemodialysis (HD) for treatment of acute life-threatening hyperammonemia. HD was performed via catheters placed in each femoral vein serving as vascular access. The tip of one of the catheters (aspirating line) was in the left external iliac vein and the tip of the other catheter (the return line) was in the inferior vena cava (IVC). High blood flow rates were used in order to rapidly lower the blood ammonia (NH3) levels. However, unanticipated marked recirculation in the IVC, between the dialysis aspirating and return catheters, was encountered, preventing significant reduction in blood NH3. The recognition of this problem, suggested solutions, and prevention are described.

Original languageEnglish (US)
Pages (from-to)592-595
Number of pages4
JournalPediatric Nephrology
Volume12
Issue number7
DOIs
StatePublished - Sep 1 1998

Fingerprint

Hyperammonemia
Renal Dialysis
Catheters
Inferior Vena Cava
Carbamyl Phosphate
Iliac Vein
Emergency Treatment
Femoral Vein
Therapeutics
Ligases
Ammonia
Blood Vessels
Dialysis

Keywords

  • Carbamoyl phosphate synthetase deficiency
  • Clearance
  • Hemodialysis
  • Hyperammonemia
  • Recirculation

Cite this

Hemodialysis catheter placement and recirculation in treatment of hyperammonemia. / Vats, Abhay; Kashtan, Clifford; Tuchman, Mendel; Mauer, Michael.

In: Pediatric Nephrology, Vol. 12, No. 7, 01.09.1998, p. 592-595.

Research output: Contribution to journalArticle

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