Hematopoietic stem-cell transplantation from an unrelated donor

Philip Mcglave, Peter A. Cassileth

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

When an HLA-matched sibling is not available and nontransplant approaches have been ineffective, transplantation of hematopoietic stem cells from an unrelated donor can effect a cure in some patients with chronic myelogenous leukemia. Even when successful, however, transplantation is a rigorous and prolonged process whose complications include infection and graft-versus-host disease. Improvements in hematopoietic stem-cell transplantation as well as innovative nontransplant approaches may improve the outcome in these patients.

Original languageEnglish (US)
Pages (from-to)43-56
Number of pages14
JournalHospital practice
Volume35
Issue number8
DOIs
StatePublished - Aug 15 2000

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