Abstract
When an HLA-matched sibling is not available and nontransplant approaches have been ineffective, transplantation of hematopoietic stem cells from an unrelated donor can effect a cure in some patients with chronic myelogenous leukemia. Even when successful, however, transplantation is a rigorous and prolonged process whose complications include infection and graft-versus-host disease. Improvements in hematopoietic stem-cell transplantation as well as innovative nontransplant approaches may improve the outcome in these patients.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 43-56 |
| Number of pages | 14 |
| Journal | Hospital practice |
| Volume | 35 |
| Issue number | 8 |
| DOIs | |
| State | Published - Aug 15 2000 |
Bibliographical note
Funding Information:Dr. McGiave Is C. J. Watson Professor of Medicine and Director, Division of Hematology, Oncology, and Transplantation, University of Minnesota Medical Schooi--Minneapolis, and Associate Director for Experimental Therapeutics, Uni-'lllrsity of Minnesota Cancer Canter. His work is supported by NIH grants PO I CA6S.ol93 and P30CA77598. Dr. Cassileth is Professor and Chair, Division of Hematology-Oncology, Department of Medicine, University of Miami School of Medicine.