Hematin therapy in porphyric attacks

C. A. Pierach; I. Bossenmaier; R. Cardinal; M. Weimer; C. J. Watson

doi:10.1007/BF01491103

Hematin therapy in porphyric attacks

C. A. Pierach, I. Bossenmaier, R. Cardinal, M. Weimer, C. J. Watson

Medicine - Administration

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Abstract

We report our experience with hematin in the treatment of 57 patients in porphyric attacks. The ratio of acute intermittent porphyria: variegate porphyria: hereditary coproporphyria was 43:11:3. More than 90% of the patients showed not only a decline in their porphyrin precursors, but also a favorable clinical response. Hematin was well tolerated and should be considered the treatment of choice in porphyric relapse.

Original language	English (US)
Pages (from-to)	829-832
Number of pages	4
Journal	Klinische Wochenschrift
Volume	58
Issue number	16
DOIs	https://doi.org/10.1007/BF01491103
State	Published - Aug 1980

Keywords

Hematin
Porphyria
Porphyrin precursors

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10.1007/BF01491103

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abstract = "We report our experience with hematin in the treatment of 57 patients in porphyric attacks. The ratio of acute intermittent porphyria: variegate porphyria: hereditary coproporphyria was 43:11:3. More than 90% of the patients showed not only a decline in their porphyrin precursors, but also a favorable clinical response. Hematin was well tolerated and should be considered the treatment of choice in porphyric relapse.",

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AU - Pierach, C. A.

AU - Bossenmaier, I.

AU - Cardinal, R.

AU - Weimer, M.

AU - Watson, C. J.

PY - 1980/8

Y1 - 1980/8

N2 - We report our experience with hematin in the treatment of 57 patients in porphyric attacks. The ratio of acute intermittent porphyria: variegate porphyria: hereditary coproporphyria was 43:11:3. More than 90% of the patients showed not only a decline in their porphyrin precursors, but also a favorable clinical response. Hematin was well tolerated and should be considered the treatment of choice in porphyric relapse.

AB - We report our experience with hematin in the treatment of 57 patients in porphyric attacks. The ratio of acute intermittent porphyria: variegate porphyria: hereditary coproporphyria was 43:11:3. More than 90% of the patients showed not only a decline in their porphyrin precursors, but also a favorable clinical response. Hematin was well tolerated and should be considered the treatment of choice in porphyric relapse.

KW - Hematin

KW - Porphyria

KW - Porphyrin precursors

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JF - Klinische Wochenschrift

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ER -

Hematin therapy in porphyric attacks

Abstract

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